Protein Alignment CG1677 and zc3h18

DIOPT Version :9

• Sequence 1: NP_001284976.1
• Gene: CG1677 / 31662
• FlyBaseID: FBgn0029941
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: NP_001037804.1
• Gene: zc3h18 / 555770
• ZFINID: ZDB-GENE-050419-13
• Length: 1148
• Species: Danio rerio
• Alignment Length: 1333
• Identity: 309/1333 - (23%)
• Similarity: 456/1333 - (34%)
• Gaps: 552/1333 - (41%)

  Fly     5 MESDDSHASSASNSSESRSNSPTNDKDEVVADHGGESPGGGGDPILDRSDRAPSTSSSSSNSSSS 69
            :||.:|.|.:....|:|..   .||.:..|.:|||:|...      || ||.|:
Zfish    27 LESPESPAEADKGVSDSEL---LNDDENEVPEHGGDSDSE------DR-DRQPA----------- 70

  Fly    70 SNRSDLSKKQKKSSSSSSGSGSGSGSSSSSGSSSEDEGDQEPEQ----EVQRLSEQQRE--QQQH 128
                                                 |.::||:    |..:|..::||  .||.
Zfish    71 -------------------------------------GREDPEELSDVEDYKLDREEREDIHQQE 98

  Fly   129 SPINERE---------SESAAGTPVNADQPGSPNAKSQPSSFLSSVRSRSVSPQLYNQAAVDLNI 184
            ..:..:|         .|....||.:.| |.||.|:.:          |..:|
Zfish    99 GALRVQEIAQKAIKSPEEEILETPRSPD-PVSPAAEHE----------RPFTP------------ 140

  Fly   185 SHDDLSDVSDIEGEEKRTSSKNSMRPADENEDGAISNDSLPTLGEEDEVEQKQSTPNGKASSGDE 249
            :.::..| .|.|.||..|::|:.:..|:..|             ||||.|:::..........|.
Zfish   141 AEEERGD-DDEEEEEDETTTKSGLGQAELEE-------------EEDEEEERRRRRRAAMVVSDL 191

  Fly   250 KEPFAKETHTDDASNGLAPATALQEDLVKTHDDDALDFEAEEGECPEQA--KEPSPMESTANETN 312
            |         |::|        :..||    |:..||::.|..|.|..|  :|..|.:....|.
Zfish   192 K---------DESS--------VSRDL----DEHELDYDEEVPEEPSAAAPEEDEPEKPAVGED- 234

  Fly   313 QTKSTTKVSQDEGDDDGEVDKDGDDKD------GDDKDT--RKDGAGNGCLED---GAGNDS--- 363
                    .:||.::|.|.:|....|:      .|::||  ||.       ||   |...||
Zfish   235 --------GEDEEEEDEEEEKRRKRKERKPILPPDNRDTPLRKS-------EDSREGGRRDSFRD 284

  Fly   364 RKDDAGNGCLEEGEEEKDIVSVSTSSSQEKVEEGELEEGEVSDEDEKRPEETEPKPVCRFYTR-- 426
            :|.:..:|.::|||                :::.:||||||.|..:::   ..|:|:|||:.:
Zfish   285 KKKEEDDGEIDEGE----------------IDDDDLEEGEVKDPMDRK---IRPRPICRFFMKGS 330

  Fly   427 ---------------------GQCTWGMSCRFLHPGVTDKGNYTMFDNVIRPVPMQGGSTGASAP 470
                                 |.|||||.|||:||||.|||||::   :.:|.|.
Zfish   331 FVTMYGNVKFFFFKSYLVFLTGNCTWGMICRFIHPGVNDKGNYSL---ISKPDPF---------- 382

  Fly   471 AAPSSTAAPRAGGSAYSSHASATADYHDYRTERPLHHRPPLLHAPSIYGAPVHDARTLLPDGAPV 535
               |...||..|.:....|                    ||:.| :.:|||..:.   ||...|.
Zfish   383 ---SPNGAPPGGAAGGGPH--------------------PLMPA-NPWGAPAVEE---LPPPPPP 420

  Fly   536 V---VENAWERGLRTAKEMMRKANKRKEQDMDFEDKKMNLTLSPD--EMEKDSYYLKDRGGSSAR 595
            :   ||:|||||||.|||:::||..||||:.|||:|:..:|:..|  :.:|::.:.::|||...
Zfish   421 LDPPVESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDRDFDKENDFFRERGGYRI- 484

  Fly   596 SPPPPSANVREQPLNPLSMP-LSMHPHAVAHANPRALLPLQYS----VYGPPPDRYGRPQYMPPQ 655
                 :..:|:...:|...| ......|...........:||:    .|.|..:|...|:....:
Zfish   485 -----TREIRDAGSDPYGDPYYDYEMEAFWRGGQYENFRVQYTETPLPYYPDRERERDPRERHRE 544

  Fly   656 YD---DVDAYGRMTRYRELPPHRMPHYEDDR---------------------RSRPTREVIVQRV 696
            .:   :.|...|..|.||....|....|.|.                     |.||.||...::.
Zfish   545 RERERERDHRERERRQREREREREREREKDSRRRKDEWDRDRLKRDEKEGRPRERPLREPREKKD 609

  Fly   697 E-----------------------------AAGRGDEWSDPWMRSKSVGR-----GSYEREDRRR 727
            |                             ...|.|||:|||.||||..|     ||..|..||.
Zfish   610 EKEKTLKPRSPTNMPPRGPMEPPTKKDMLSVTKRPDEWNDPWCRSKSPRRRPGFMGSPPRGRRRH 674

  Fly   728 RDRRSYSSNSSYSTSNSSQSDSSSDS--------SRSSSPSDHKRRYGSHKLA-TATATSRRHGG 783
            |     .|.||.|.||||:|.|.|.|        |||.|.|.....|.||... ::.:.||...|
Zfish   675 R-----PSGSSVSLSNSSRSSSRSSSFTGSGSSRSRSRSRSSSMSSYSSHSSQHSSFSGSRSRSG 734

  Fly   784 RAARSPSQIPRRPRRTSK-----------------GSLSPSYK---------RPAV-DKRGVGHS 821
            ..:.|||..|...|..:|                 |:|.|..:         .|:: ::.|....
Zfish   735 SFSSSPSPSPSAQRNANKNKAEQPPAAAKGPPLKPGALPPPRRDKGPPKVMPSPSLPEQPGKPPK 799

  Fly   822 PSSKRKKLSSPAP-------------------KKFDKLR----RRRSSSSSDSDSSDTSYSDSES 863
            |.::..|..:|.|                   :|.::.:    |||:.|.|.|.|   |||.|.|
Zfish   800 PITETVKPPNPRPPGRPPGPREPREPPNMREGRKKERQQHNPPRRRTVSGSVSGS---SYSGSSS 861

  Fly   864 GS-SSSDSSSGSRETPQKRVRATDKALNERKLISKPAEQSTKKRSPISIEIKKTSNMVG--VSAL 925
            .| |.|.|:|.||....|     .::|:    :|..:..|:...|..|:....:.:|..  .|.:
Zfish   862 RSRSRSSSASASRSGSHK-----SRSLS----VSSVSSVSSASSSSSSVRSADSDDMYADLASPV 917

  Fly   926 ASASNSADSDAEKDHDNGKDKEKDHVKEKDKDCKEKDKDKDGMK--------------------- 969
            :|||:.:.:......|.|..:|:...||:.|..|:.:..||..|
Zfish   918 SSASSRSPTPGHPRKDRGPPRERGPNKERGKPPKKDEPFKDERKRVDPSGLPSKASSDMPRSGNR 982

  Fly   970 ------------------------------------------DKE-------------------- 972
                                                      |||
Zfish   983 GHPMHPPPMGPPGGYGSHKDIKLTLLNKQQTDRSNRKRYFPSDKERPPSPLRKRMAMSPDGGRDR 1047

  Fly   973 ----------------------------------------------------------------- 972
                                                                             
Zfish  1048 RMPGRPPMSPRMERPKGQGPRPMPSQGERKRPLSPPAKSSGKGPAAASAAKPPAPGAGSGSASGS 1112

  Fly   973 --GKK----SRREELLKQLRAVEDAIAKKRSKL 999
              ||.    ||||||||||:|||||||:||:|:
Zfish  1113 APGKPSSTLSRREELLKQLKAVEDAIARKRAKI 1145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1677	NP_001284976.1	ZnF_C3H1	419..440	CDD:214632	13/43 (30%)
zc3h18	NP_001037804.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..315		96/435 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..417		14/73 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	521..1127		125/622 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595618
Domainoid	1	1.000	101	1.000	Domainoid score	I6938
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4102
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008353
OrthoInspector	1	1.000	-	-		oto40507
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46582
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6400
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.110