DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1677 and PNUTS

DIOPT Version :9

Sequence 1:	NP_001284976.1	Gene:	CG1677 / 31662	FlyBaseID:	FBgn0029941	Length:	1000	Species:	Drosophila melanogaster
Sequence 2:	NP_001014453.1	Gene:	PNUTS / 33270	FlyBaseID:	FBgn0053526	Length:	1135	Species:	Drosophila melanogaster

Alignment Length:	762	Identity:	179/762 - (23%)
Similarity:	267/762 - (35%)	Gaps:	206/762 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SDDSHASSASNSSESRSNSPTNDKDEVVADHGGESPGGGGDPILDRSDRAPSTSSSSS------- 64
            |..||.||:|:||.|..:|.:.......:.|...|     |...|: |:|.|:|.|||
  Fly   311 SSSSHKSSSSSSSSSSKSSSSKSSSSSSSSHRSSS-----DKYRDK-DKARSSSGSSSSSKDRER 369

  Fly    65 NSSSSSNRSDLSKKQKKSSSSSSGSGSGSGSSSS---------SGSSSEDEGDQEPEQEVQRLSE 120
            :|.|||:.|:..|..|.||||||.|.|.||||||         |.|||....|::.:.::.
  Fly   370 SSGSSSSSSNKHKSSKSSSSSSSSSSSSSGSSSSKDRKSSSSTSSSSSSSRQDKDKDNKLM---- 430

  Fly   121 QQREQQQHSPINERESESAAGTPVNADQPGSPNAKSQPSSFLSSVRSRSVSPQLYNQAAVDLNIS 185
                     |.....:.:||||        ||.|.::.|   .:.:.||: |.:..:|::.:.|.
  Fly   431 ---------PPPAVAASNAAGT--------SPTASAKES---DAQKPRSI-PIMSRKASISIEIR 474

  Fly   186 HD---------------------DLSDVSDIEGEEKRTSSKNSMRPADENEDGAISNDSLPTLGE 229
            .|                     :.......:|.:|.|||..:..||         ..::|:
  Fly   475 RDTEKTATVKTYQSKFRSHGLTEEAPPPPSRKGLKKPTSSAVAASPA---------LMAVPS--- 527

  Fly   230 EDEVEQKQSTPNGKASSGDEKEPF-----AKETHTDDASNGLAPATALQEDLVKTH-DDDALDFE 288
                ..|:.:|..:..|.|:|...     |.......|:..:||...  :.||:|: ..|||...
  Fly   528 ----SLKRPSPPPRDLSTDKKAKIDINNVAGHVERPGAAKLIAPKKI--QTLVETNLFSDALAAS 586

  Fly   289 AE----------EGECPEQAKEP-SPMESTANETNQTKSTTKVSQDEG--DDDGEVDKDGDDKDG 340
            .|          ....|.....| :|::...:..:::||..| |.|..  :||......|.|.|.
  Fly   587 IEPKKVVKRKRTSATSPTDKDAPLAPLKFYQDTLDESKSEEK-SDDSSKENDDARSSSPGKDTDA 650

  Fly   341 DDKD---------------TRKDGAGNGCLEDGAGNDSRKD------DAGNGCLEEG-------E 377
            ||.|               ..|..||....|.|..:|:.:|      ..|.||..:|       .
  Fly   651 DDDDIPLKRVKEDIEQKVQKAKAAAGGEGGEAGNTSDNAEDLPEEPKKPGPGCGPDGPPGVLTLH 715

  Fly   378 EEKDIVSVSTSSSQEKVEEGELEEGEVSDE-DEKRPEETEPKPVCRFYTRGQCTWGMSCRFLHPG 441
            ..|......|..|:||:.:....|.:.|:. :..:....|.|.:.||..|...|
  Fly   716 RRKGPKKKLTWQSEEKLTQIRYFEVDRSERVNVMKQTFLEMKNMERFSERDALT----------- 769

  Fly   442 VTDKGNYTMFDNVIRPVPMQGGSTGASAPAAPSSTAAPRAGGSAYSSHASATADYHDYRTERPLH 506
            :..:|    ||:.:.| .|:.      .|............|: .|.......| .:..|.|.|:
  Fly   770 IARRG----FDDTMEP-QMEW------RPLLEVDNVPDHPNGN-LSKQRQVQMD-REATTLRALY 821

  Fly   507 HRPPLL-HAPSIYGAPVHDARTL--LP----DGAPVVVEN----AWERGLRTAKEMMRKANKRKE 560
            ..|.:: .:|:......|.|..:  :|    .|.|..|.:    ||....:.|......|| ...
  Fly   822 FSPDMIPDSPAEAELEPHFAHDIPVIPMDDLTGNPDAVNDYSALAWPEPKKYAPSSGVGAN-ISG 885

  Fly   561 QDMDFEDKKM-NLTLSPDEMEK--DSYYLKDRGGSSARSPPPPSANVREQPLNPLSMPLSMHPHA 622
            .||.|.|..: .|...|:.|:.  |.:    .||..|.:..||..|              |.|:.
  Fly   886 SDMGFNDNMLTGLGAGPNLMQNPFDPF----MGGMPAPTGMPPGPN--------------MMPNQ 932

  Fly   623 VAHANPRALLPLQYSVYGPP--PDRYGRP------------QYMPPQ 655
            |.:..|:........|.|||  |.....|            ..||||
  Fly   933 VPNGTPQIWQNQMGPVGGPPGVPPMMNGPGGPGMDMSNMNMNNMPPQ 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1677	NP_001284976.1	ZnF_C3H1	419..440	CDD:214632	4/20 (20%)
PNUTS	NP_001014453.1	Med26	92..142	CDD:285873
PNUTS	NP_001014453.1	ZnF_C3H1	1110..1130	CDD:214632
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930