DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9650 and ZNF700

DIOPT Version :9

Sequence 1:NP_001356899.1 Gene:CG9650 / 31660 FlyBaseID:FBgn0029939 Length:1254 Species:Drosophila melanogaster
Sequence 2:NP_001258777.1 Gene:ZNF700 / 90592 HGNCID:25292 Length:745 Species:Homo sapiens


Alignment Length:474 Identity:111/474 - (23%)
Similarity:161/474 - (33%) Gaps:160/474 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   717 YSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACD---------------------FEC------ 754
            |.|..|.|.|.:...|.||:|||||||||:|:.||                     ::|      
Human   253 YECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKA 317

  Fly   755 -SHIQKLMKHMRVHRSPADDQDNQDNQDDG-SNADSLETN-EADNDEDPNPDESEEELGDGDNDP 816
             ::...|.:|.|.|......:..|  ..:| |...|.:|: ..::.|.|                
Human   318 FAYTSSLRRHERTHSGKKPYECKQ--YGEGLSYLISFQTHIRMNSGERP---------------- 364

  Fly   817 DGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKS-QSPKTTSSGATSLVGELMDK----- 875
                                   ||.       :|.||. .|.|:..:...:..||...|     
Human   365 -----------------------YKC-------KICGKGFYSAKSFQTHEKTHTGEKRYKCKQCG 399

  Fly   876 --FGLSNIAQYSEAYKQALQESGRK--EAAAAAAAAAAAADNNNRGGAGA---PLSDKLNG---L 930
              |.||:..:|.|..     .:|.|  |......|..:|:.....||...   |...|..|   .
Human   400 KAFNLSSSFRYHERI-----HTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFR 459

  Fly   931 PVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEA 995
            ..:.||:..........::..:.|.|...|.......   ...|.::|..|:             
Human   460 STSHLRVHGRTHTGEKPYECKECGKAFRYVKHLQIHE---RTEKHIRMPSGE------------- 508

  Fly   996 LFENLKLKPL-------GLGGANSLIQGPLLKKESRQRNDT------CEFCGKVFKNCSNLTVHR 1047
                   :|.       |...|.|.        ::.::..|      |..|||.|:.|::|..|.
Human   509 -------RPYKCSICEKGFYSAKSF--------QTHEKTHTGEKPYECNQCGKAFRCCNSLRYHE 558

  Fly  1048 RSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMR------ 1106
            |:|||||||:|:.|..|...:|.|..|.:||  ||:..|.|:.|...||..|.|.||.|      
Human   559 RTHTGEKPYECKQCGKAFRSASHLRMHERTH--TGEKPYECKQCGKAFSCASNLRKHGRTHTGEK 621

  Fly  1107 -----KCVVNQGKAAAAAN 1120
                 :|    |||..:|:
Human   622 PYECKQC----GKAFRSAS 636

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9650NP_001356899.1 zf-C2H2 717..739 CDD:333835 9/21 (43%)
C2H2 Zn finger 719..739 CDD:275368 8/19 (42%)
zf-H2C2_2 731..756 CDD:338759 16/52 (31%)
C2H2 Zn finger 747..767 CDD:275368 7/47 (15%)
zf-C2H2 1029..1050 CDD:333835 10/26 (38%)
C2H2 Zn finger 1030..1050 CDD:275368 9/19 (47%)
zf-H2C2_2 1042..1067 CDD:338759 13/24 (54%)
C2H2 Zn finger 1058..1078 CDD:275368 6/19 (32%)
C2H2 Zn finger 1088..1106 CDD:275368 8/17 (47%)
ZNF700NP_001258777.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
KRAB 27..>69 CDD:214630
KRAB 27..66 CDD:279668
C2H2 Zn finger 169..191 CDD:275368
C2H2 Zn finger 199..219 CDD:275368
COG5048 224..636 CDD:227381 110/472 (23%)
C2H2 Zn finger 227..247 CDD:275368
zf-H2C2_2 243..264 CDD:290200 5/10 (50%)
C2H2 Zn finger 255..275 CDD:275368 8/19 (42%)
zf-H2C2_2 268..292 CDD:290200 15/23 (65%)
C2H2 Zn finger 283..303 CDD:275368 3/19 (16%)
zf-H2C2_2 298..320 CDD:290200 1/21 (5%)
C2H2 Zn finger 311..331 CDD:275368 4/19 (21%)
C2H2 Zn finger 367..387 CDD:275368 5/26 (19%)
zf-H2C2_2 379..403 CDD:290200 3/23 (13%)
C2H2 Zn finger 395..415 CDD:275368 5/24 (21%)
zf-H2C2_2 407..432 CDD:290200 6/29 (21%)
C2H2 Zn finger 423..443 CDD:275368 4/19 (21%)
C2H2 Zn finger 451..471 CDD:275368 4/19 (21%)
zf-H2C2_2 463..488 CDD:290200 4/24 (17%)
C2H2 Zn finger 479..498 CDD:275368 3/21 (14%)
C2H2 Zn finger 513..533 CDD:275368 3/27 (11%)
zf-H2C2_2 525..550 CDD:290200 7/32 (22%)
C2H2 Zn finger 541..561 CDD:275368 9/19 (47%)
zf-H2C2_2 553..578 CDD:290200 13/24 (54%)
C2H2 Zn finger 569..589 CDD:275368 6/19 (32%)
zf-H2C2_2 581..606 CDD:290200 10/26 (38%)
C2H2 Zn finger 597..617 CDD:275368 9/19 (47%)
zf-H2C2_2 609..634 CDD:290200 8/28 (29%)
C2H2 Zn finger 625..645 CDD:275368 5/16 (31%)
zf-H2C2_2 637..660 CDD:290200 111/474 (23%)
C2H2 Zn finger 653..673 CDD:275368
C2H2 Zn finger 681..701 CDD:275368
C2H2 Zn finger 709..729 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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