DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9650 and ZNF85

DIOPT Version :9

Sequence 1:NP_001356899.1 Gene:CG9650 / 31660 FlyBaseID:FBgn0029939 Length:1254 Species:Drosophila melanogaster
Sequence 2:XP_011526565.1 Gene:ZNF85 / 7639 HGNCID:13160 Length:640 Species:Homo sapiens


Alignment Length:432 Identity:102/432 - (23%)
Similarity:149/432 - (34%) Gaps:105/432 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   717 YSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRS----PADDQDNQ 777
            |.|..|.|.|.:.:.|..|:|.|||||||||..|....:....|:||.::|..    ..::....
Human   247 YKCEECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKT 311

  Fly   778 DNQDDGSNADSL-----------ETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDE 831
            .|:........:           |..:|.|.........:...|                |...:
Human   312 FNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTG----------------EKPYK 360

  Fly   832 LEECEDMDYKAEDLSVSNRIDGKSQSP-------KTTSSGATSLVGELM---------DKFGLSN 880
            .|||.....::.:|: :::|....:.|       |..:..|.....|::         :|.|.: 
Human   361 CEECGKAFKQSSNLT-THKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKA- 423

  Fly   881 IAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNC 945
            ...:|......:..:|.|.......            |.....|..|....:.....:....|.|
Human   424 FNHFSHLTTHKIIHTGEKPYKCKEC------------GKAFKHSSTLTKHKIIHTGEKPYKCKEC 476

  Fly   946 -NMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGG 1009
             ..|.|   ....::....:....|:|..|     .|..:..|..|.|::               
Human   477 EKAFNQ---SSKLTEHKKIHTGEKPYECEK-----CGKAFNQSSNLTRHK--------------- 518

  Fly  1010 ANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRH 1074
                      |..:.::...||.|||.||..|.||:|:..||||||||||.|..|..||||||:|
Human   519 ----------KSHTEEKPYKCEECGKGFKWPSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKH 573

  Fly  1075 MKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMR--------KC 1108
            .|.|  ||:..|.|..|...|:..|.|.||.|        ||
Human   574 KKIH--TGEKPYTCEECGKAFNQSSNLTKHKRIHTGEKPYKC 613

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9650NP_001356899.1 zf-C2H2 717..739 CDD:333835 8/21 (38%)
C2H2 Zn finger 719..739 CDD:275368 7/19 (37%)
zf-H2C2_2 731..756 CDD:338759 13/24 (54%)
C2H2 Zn finger 747..767 CDD:275368 5/19 (26%)
zf-C2H2 1029..1050 CDD:333835 11/20 (55%)
C2H2 Zn finger 1030..1050 CDD:275368 11/19 (58%)
zf-H2C2_2 1042..1067 CDD:338759 15/24 (63%)
C2H2 Zn finger 1058..1078 CDD:275368 12/19 (63%)
C2H2 Zn finger 1088..1106 CDD:275368 7/17 (41%)
ZNF85XP_011526565.1 KRAB 4..64 CDD:214630
KRAB 4..43 CDD:279668
COG5048 189..603 CDD:227381 99/420 (24%)
C2H2 Zn finger 221..241 CDD:275368
C2H2 Zn finger 249..269 CDD:275368 7/19 (37%)
zf-H2C2_2 262..286 CDD:290200 13/23 (57%)
C2H2 Zn finger 277..297 CDD:275368 5/19 (26%)
zf-H2C2_2 289..314 CDD:290200 4/24 (17%)
C2H2 Zn finger 305..325 CDD:275368 1/19 (5%)
zf-H2C2_2 318..342 CDD:290200 2/23 (9%)
C2H2 Zn finger 333..353 CDD:275368 3/19 (16%)
zf-H2C2_2 346..370 CDD:290200 5/39 (13%)
C2H2 Zn finger 361..381 CDD:275368 5/20 (25%)
zf-H2C2_2 373..398 CDD:290200 4/25 (16%)
C2H2 Zn finger 389..409 CDD:275368 3/19 (16%)
zf-H2C2_2 401..426 CDD:290200 3/25 (12%)
C2H2 Zn finger 417..437 CDD:275368 3/20 (15%)
zf-H2C2_2 429..454 CDD:290200 3/36 (8%)
C2H2 Zn finger 445..465 CDD:275368 3/31 (10%)
zf-H2C2_2 458..482 CDD:290200 4/23 (17%)
C2H2 Zn finger 473..493 CDD:275368 4/22 (18%)
zf-H2C2_2 486..510 CDD:290200 4/28 (14%)
C2H2 Zn finger 501..521 CDD:275368 6/49 (12%)
zf-H2C2_2 513..537 CDD:290200 8/48 (17%)
C2H2 Zn finger 529..549 CDD:275368 11/19 (58%)
zf-H2C2_2 542..566 CDD:290200 15/23 (65%)
C2H2 Zn finger 557..577 CDD:275368 12/19 (63%)
zf-H2C2_2 570..594 CDD:290200 11/25 (44%)
C2H2 Zn finger 585..605 CDD:275368 8/19 (42%)
zf-H2C2_2 597..621 CDD:290200 6/17 (35%)
C2H2 Zn finger 613..633 CDD:275368 1/1 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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