DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9650 and ZNF708

DIOPT Version :9

Sequence 1:	NP_001356899.1	Gene:	CG9650 / 31660	FlyBaseID:	FBgn0029939	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	XP_016882693.1	Gene:	ZNF708 / 7562	HGNCID:	12945	Length:	587	Species:	Homo sapiens

Alignment Length:	401	Identity:	90/401 - (22%)
Similarity:	127/401 - (31%)	Gaps:	153/401 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 QEPIAHC----YSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSP 770
            |..|.|.    |.|..|.|.|:..:||..|:..|||||||||..|....:....|.:|..:|..
Human   185 QHEIIHTGEKPYKCEECGKAFKKSSNLTNHKIIHTGEKPYKCEECGKAFNQSSTLTRHKIIHTG- 248

  Fly   771 ADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEEC 835
                                                                       ::|.:|
Human   249 -----------------------------------------------------------EKLYKC 254

  Fly   836 EDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEA 900
            |:.              ||:                    |..|     |...|..:..:|.|..
Human   255 EEC--------------GKA--------------------FNRS-----SNLTKHKIVHTGEKPY 280

  Fly   901 AAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNP 965
            .......|....:|        |::.                |..:..::|...|...:.
Human   281 KCEECGKAFKQSSN--------LTNH----------------KKIHTGEKPYKCGECGKA----- 316

  Fly   966 FPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGA--NSLIQGPLLKKESRQRND 1028
                |.||..:.        ..:.:|..|..:   |.:..|...:  ::|.:..::..|.:...
Human   317 ----FTLSSHLT--------THKRIHTGEKPY---KCEECGKAFSVFSTLTKHKIIHTEEKPYK- 365

  Fly  1029 TCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDM 1093
             ||.|||.|...|:||.|:..||||||||||.|..|..:||.||.|...|  |||..|:|..|..
Human   366 -CEECGKAFNRSSHLTNHKVIHTGEKPYKCEECGKAFTKSSTLTYHKVIH--TGKKPYKCEECGK 427

  Fly  1094 PFSVPSTLEKH 1104
            .||:.|.|.||
Human   428 AFSIFSILTKH 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9650	NP_001356899.1	zf-C2H2	717..739	CDD:333835	8/21 (38%)
		C2H2 Zn finger	719..739	CDD:275368	7/19 (37%)
		zf-H2C2_2	731..756	CDD:338759	13/24 (54%)
		C2H2 Zn finger	747..767	CDD:275368	4/19 (21%)
		zf-C2H2	1029..1050	CDD:333835	10/20 (50%)
		C2H2 Zn finger	1030..1050	CDD:275368	10/19 (53%)
		zf-H2C2_2	1042..1067	CDD:338759	15/24 (63%)
		C2H2 Zn finger	1058..1078	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1088..1106	CDD:275368	8/17 (47%)
ZNF708	XP_016882693.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000