Protein Alignment Cph and sall3a

DIOPT Version :10

• Sequence 1: NP_001356899.1
• Gene: Cph / 31660
• FlyBaseID: FBgn0029939
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: XP_068074900.2
• Gene: sall3a / 560775
• ZFINID: ZDB-GENE-020228-4
• Length: 1372
• Species: Danio rerio
• Alignment Length: 1537
• Identity: 284/1537 - (18%)
• Similarity: 475/1537 - (30%)
• Gaps: 520/1537 - (33%)

  Fly     5 MLSISEDH-GFRSLSHSDSTENDAVATQDILTC-GACQKAFALSDIVKFIQHKVLQCNKENYGQC 67
            :|.:..:| ....:..|||.......:::...| ..|.:.|..||   |.:| :..|.|......
Zfish    20 LLELLPEHVSGEGVDDSDSGNESRSGSEETHVCEKCCAEFFKWSD---FCEH-LKTCTKNPLVLI 80

  Fly    68 ATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSR 132
            .:.|......|::..|      .||   |:....|.||::..||..:.........|........
Zfish    81 ISDNEVTSDPAQDYLP------EPS---PVPSCVSDPANSEDAVEVSHMPTEGDEGAEMMLESGA 136

  Fly   133 IHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLD-----SNAAPSSPA-------- 184
            :......|.::     ..:|::.:|.:|..|..:.:.....|:     |.|..|.|:
Zfish   137 VLEKEDEPMEV-----ELSPEKPIDPDDPVTLAEPDISLPPLEDHKQSSGAGYSIPSTNVTLETL 196

  Fly   185 -----AIERQSSG------------------DSSCEMEEQQDRQDK---QSQPKQAKVKQEPYDE 223
                 |:.:.|.|                  |....:::||.||.|   |.:.:.|.:..:...:
Zfish   197 HGTRVAVAQFSQGARGALASEVSTMAIPMILDQLMALQQQQLRQLKLIEQIRSQVALINNQAPTQ 261

  Fly   224 EGVNHHQNQDDDDDEEMEERSLAKRPKME-------LVDAEANTVHTEPSNYTCSTCKTRYTSAW 281
            ..|:|  ..|...:..::..|.:..|.|.       .:....|.:|.:..|..
Zfish   262 TAVSH--KVDHSINAALQVPSSSSIPAMPGQLHLRGFITPPINQLHMKGPNSL------------ 312

  Fly   282 RLIQHVQHSHGVKIYVE------SPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAV 340
                :||.|..|...::      ||.||   .:|:....:|.|:   .:....:::|::...|..
Zfish   313 ----NVQASVAVSSALDVACTSGSPAGG---QLASSGMKSNIAI---NSLYPTTSNGVSPQMPPC 367

  Fly   341 SPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQA 405
            |  .:::||:..||..|..|......|:.....:.|..|.|..:::.||:
Zfish   368 S--VSISSSSCTSSSTGTGGEINCGISLPRNTPSPLTLTHGRLLTSPSSL--------------- 415

  Fly   406 QQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEA---MHANPFQLLRM------PLPPALAQAGN 461
                                      ||:|...:   :..||...:..      ||...:.....
Zfish   416 --------------------------PLVPHSSSNSVIFPNPLASIAATTNALDPLSALMKHRKG 454

  Fly   462 VVPTVAPLFGRPSPADHYRMEQLVSEQFRH------------HGFNLAAAAAAAQAQFNANGQVV 514
            ..|.|:....:||..|.:         |:|            ....:...:...:..|..|  :.
Zfish   455 KPPNVSVFDTKPSSEDPF---------FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCN--IC 508

  Fly   515 GGVVSGSG------------------EPRPPSS------SSSGSQRG-SVPP-----------AA 543
            |...|..|                  .|.|...      :|||...| |:||           ..
Zfish   509 GNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTSSGIPYGMSLPPEKPVTTWLDSKPI 573

  Fly   544 LP--PPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKL 606
            ||  |.|:                                    :.|.....|.::|..|.|...
Zfish   574 LPTIPTSV------------------------------------ALQLPPTIPSIIGSYGDSTSF 602

  Fly   607 EPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSP----SQQQQQQLATIPRP 667
            .|.              ..||        ..|||   .|....|.||    ::....|:::.|:|
Zfish   603 SPL--------------NRSP--------QRPSP---PSSECTSLSPNHLITETSIAQISSSPQP 642

  Fly   668 H--SLTP----PEKL----------GDASSENGSLGLILAST--PRSASTPPSKTGDVSLQEPIA 714
            :  |.||    ||.|          |:.|....|:..::::|  ..:.||....|..|:....::
Zfish   643 NLASNTPPVLKPEALHLPANSTTRPGETSISTTSISQVISTTIVTTTCSTRTQLTDPVNSSSAVS 707

  Fly   715 H--------------------------------------------CYSCSYCDKKFRFENNLIIH 735
            |                                            ...|..|.:....::.|.:|
Zfish   708 HPSLQISLNQFKPKFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMH 772

  Fly   736 QRTHTGEKPYKCTAC-------------------------DFECSHIQK-------LMKHMRVH- 767
            .|.||||:|:||..|                         ...|...||       |.:|:|:|
Zfish   773 YRIHTGERPFKCKICGRAFTTKGNLKTHFGVHRSKPPLRVQHSCPICQKKFTNAVVLQQHIRMHM 837

  Fly   768 -----RSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDE 827
                 .:|..|.....:.|...:..||:.  ..|.:|...||.::.|.|.....|.:.||..:..
Zfish   838 GGQIPNTPLPDTFQDTDADLSFDEKSLDA--MSNYDDELIDEMDQALEDETGLKDENMDLQKQLH 900

  Fly   828 DEDELEECE-------------DMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELM------ 873
            ...|:....             :.:.|..|.:| |.....|..|....||...:.|:::
Zfish   901 LYSEMSPSTSPPTSLISSIGAFENEMKLSDPAV-NITHSFSVKPTENGSGVDGVNGDMLKNDLSS 964

  Fly   874 --------------------DKFGLSNIAQYSEAYK-QALQESGRKEAAAAAAAAAAAADNNNRG 917
                                ....||.....||::: ::.|.:...:..|..:.:|.|...:.:.
Zfish   965 TLVDLENHSVGSPAQSESSGSMLALSPTYSQSESHRSKSPQANSSSKDEALTSTSAHAMVKSEQL 1029

  Fly   918 GAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQ---QPQDGG--APSQVPLFNPFPNPFELSKRMK 977
            ...:|.|:....|.:.|.:....|.|:.|.|.   ..:|.|  .||.:.         ..|..:|
Zfish  1030 DIHSPGSENTGALDLTATQPTRSFVKDENPFSLLFLGRDRGLSTPSNIS---------SESSTVK 1085

  Fly   978 MDGGDWWGMSQALHRNEALFENLKLKPLG----LGGANSLIQG---PLL-----KKESRQRNDTC 1030
            .:.|.        .:..||.|...| |:|    ...|.:.|..   |:|     ::..:|.|  |
Zfish  1086 FENGH--------SKPPALCEGPHL-PVGPQVPTATAQTTISSNITPMLAPPPPRRTPKQHN--C 1139

  Fly  1031 EFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHG-----RTGKDVYRCRF 1090
            ..|||.|.:.|.|.:|.|:||||||:.|.:|..|......|    |..|     |.|:.|:.|..
Zfish  1140 HSCGKNFSSASALQIHERTHTGEKPFGCSICGRAFTTKGNL----KEEGRWFEPRLGQLVFLCGV 1200

  Fly  1091 C-------DMPFSVPST--------------LEKHM---------RKCVVNQGKAAAAANAVAAA 1125
            |       ..|...|.:              :..||         |:..|....|....:|:..:
Zfish  1201 CMLSLHSRGFPPGAPVSPIVQRHATQVNWVHMGTHMWNNAPARRGRRLSVENPMALLGGDAIKFS 1265

  Fly  1126 QAAQ----AAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYP--PQFVSGHNLS 1184
            :..|    |.|.::........||   |:.:..|.::    .::|.:...|.|  |..:||..:.
Zfish  1266 EMFQKDLAARAINVDPGFWNQYAV---AITSGLAMKN----NEISVIQNGGIPSIPISLSGGGIP 1323

  Fly  1185 LPGSVSGD---NDSNASSSMTGV----------HPIS-LKEE 1212
            ..|.:||.   :.:.:|..:||:          ||.| .:||
Zfish  1324 AVGGMSGGIERSRTGSSPPVTGLEKTNLEMGTGHPFSRFREE 1365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cph	NP_001356899.1	zf-C2H2	717..739	CDD:395048	5/21 (24%)
		C2H2 Zn finger	719..739	CDD:275368	5/19 (26%)
		zf-H2C2_2	731..756	CDD:463886	12/49 (24%)
		C2H2 Zn finger	747..767	CDD:275368	8/51 (16%)
		zf-C2H2	1029..1050	CDD:395048	9/20 (45%)
		C2H2 Zn finger	1030..1050	CDD:275368	9/19 (47%)
		zf-H2C2_2	1042..1067	CDD:463886	12/24 (50%)
		C2H2 Zn finger	1058..1078	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1088..1106	CDD:275368	6/47 (13%)
sall3a	XP_068074900.2	None