DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9650 and Zfp35

DIOPT Version :9

Sequence 1:	NP_001356899.1	Gene:	CG9650 / 31660	FlyBaseID:	FBgn0029939	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	NP_001013159.1	Gene:	Zfp35 / 307547	RGDID:	1312031	Length:	580	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	117/512 - (22%)
Similarity:	176/512 - (34%)	Gaps:	149/512 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   717 YSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTAC---------------------DFECSHIQK- 759
            |.||:|.|.|...::||.|||.|||||||||..|                     .::|||..|
  Rat   132 YPCSWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLMTHQRIHTGEKPYQCSHCSKS 196

  Fly   760 ------LMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDG 818
                  ::||:|:|........|...:....::|.::.......|.|.
  Rat   197 FSQHSGMVKHLRIHTGEKPYMCNHCYKHFSQSSDLIKHERIHTGEKPY----------------- 244

  Fly   819 DGDLDGEDEDEDELEECEDMDYKAEDLSVSNRI-DGKSQSPKTTSSGATSLVGELMDKFGLSNIA 882
                        :.:.|.....::.|..:..|| .|:...|....:               .:.:
  Rat   245 ------------KCDVCGKAFSQSSDRILHQRIHTGEKPYPCAQCN---------------KSFS 282

  Fly   883 QYSEAYKQALQESGRKEAAAAAAAAAAAADN-----------------NNRGGAGAPLSDKLN-- 928
            |.|:..|.....:|.|....:....|....:                 |....:.:.|||.:|
  Rat   283 QNSDLIKHRRIHTGEKPYQCSECGKAFNQSSVLILHQRIHTGEKPYPCNQCAKSFSRLSDLINHQ 347

  Fly   929 -----GLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMS- 987
                 ..|....:....|::..::.:..:          .:....|:|..|     .|..:..|
  Rat   348 RIHTGEKPYPCSQCSKMFSRRSDLVKHYR----------IHTGEKPYECDK-----CGKTFSQSS 397

  Fly   988 -----QALHRNEALFENLKLKPLGLGG-ANSLIQGPLLKKESR----QRNDTCEFCGKVFKNCSN 1042
                 |.:|..|        ||..... :.|..:|..|.|..|    ::..||..|.|.|...|:
  Rat   398 NLILHQRIHTGE--------KPYPCNSCSKSFSRGSDLIKHQRVHTGEKPYTCNLCNKSFSQSSD 454

  Fly  1043 LTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMR- 1106
            ||.|:|.|:|||||.|..|:.|..|||.|..|.:.|  ||:..|.|..|...||..|.|.||.|
  Rat   455 LTKHQRVHSGEKPYHCSSCNKAFRQSSDLILHYRVH--TGERPYACTQCTRSFSQKSDLIKHQRV 517

  Fly  1107 -------KCVVNQGKAAAAANA------VAAAQAAQAAAQHIQAAAQQAQAVQAQAV 1150
                   |||.  |||.:..:|      :...:.....||..::..|::..|..|.|
  Rat   518 HTGEKPYKCVC--GKAFSQCSAFTLHQRIHTGERPYPCAQCGKSFTQRSDLVNHQRV 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9650	NP_001356899.1	zf-C2H2	717..739	CDD:333835	11/21 (52%)
		C2H2 Zn finger	719..739	CDD:275368	10/19 (53%)
		zf-H2C2_2	731..756	CDD:338759	16/45 (36%)
		C2H2 Zn finger	747..767	CDD:275368	9/47 (19%)
		zf-C2H2	1029..1050	CDD:333835	10/20 (50%)
		C2H2 Zn finger	1030..1050	CDD:275368	9/19 (47%)
		zf-H2C2_2	1042..1067	CDD:338759	13/24 (54%)
		C2H2 Zn finger	1058..1078	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1088..1106	CDD:275368	8/17 (47%)
Zfp35	NP_001013159.1	C2H2 Zn finger	80..100	CDD:275368
		COG5048	102..486	CDD:227381	90/420 (21%)
		C2H2 Zn finger	106..126	CDD:275368
		C2H2 Zn finger	134..154	CDD:275368	10/19 (53%)
		zf-H2C2_2	146..171	CDD:290200	15/24 (63%)
		C2H2 Zn finger	162..182	CDD:275368	2/19 (11%)
		zf-H2C2_2	174..199	CDD:290200	4/24 (17%)
		C2H2 Zn finger	190..210	CDD:275368	7/19 (37%)
		C2H2 Zn finger	218..238	CDD:275368	2/19 (11%)
		zf-H2C2_2	230..255	CDD:290200	4/53 (8%)
		C2H2 Zn finger	246..266	CDD:275368	3/19 (16%)
		zf-H2C2_2	262..283	CDD:290200	4/35 (11%)
		C2H2 Zn finger	274..294	CDD:275368	3/34 (9%)
		zf-H2C2_2	286..311	CDD:290200	4/24 (17%)
		C2H2 Zn finger	302..322	CDD:275368	1/19 (5%)
		zf-H2C2_2	318..339	CDD:290200	1/20 (5%)
		C2H2 Zn finger	330..350	CDD:275368	5/19 (26%)
		zf-H2C2_2	342..367	CDD:290200	4/24 (17%)
		C2H2 Zn finger	358..378	CDD:275368	1/29 (3%)
		zf-H2C2_2	370..395	CDD:290200	4/39 (10%)
		C2H2 Zn finger	386..406	CDD:275368	4/24 (17%)
		zf-H2C2_2	398..423	CDD:290200	6/32 (19%)
		C2H2 Zn finger	414..434	CDD:275368	5/19 (26%)
		zf-H2C2_2	426..451	CDD:290200	8/24 (33%)
		C2H2 Zn finger	442..462	CDD:275368	9/19 (47%)
		zf-H2C2_2	454..479	CDD:290200	13/24 (54%)
		C2H2 Zn finger	470..490	CDD:275368	8/19 (42%)
		C2H2 Zn finger	498..518	CDD:275368	9/19 (47%)
		C2H2 Zn finger	526..545	CDD:275368	6/20 (30%)
		zf-H2C2_2	541..562	CDD:290200	2/20 (10%)
		C2H2 Zn finger	553..573	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000