DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9650 and Sall2

DIOPT Version :9

Sequence 1:	NP_001356899.1	Gene:	CG9650 / 31660	FlyBaseID:	FBgn0029939	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	NP_001100732.1	Gene:	Sall2 / 305854	RGDID:	1309272	Length:	1004	Species:	Rattus norvegicus

Alignment Length:	1016	Identity:	206/1016 - (20%)
Similarity:	348/1016 - (34%)	Gaps:	278/1016 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 AASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNT-SGG----SISN 386
            :||.:|.||.:.  .|.......|:.|.|      |......::.|::..|.. .||    |.|:
  Rat    20 SASENGDASEED--HPQVCAKCCAQFSDP------TEFLAHQNACCTDPPVMVIIGGQENPSNSS 76

  Fly   387 TSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMP 451
            .||:..|:           ...:.:|...:..||..:.::|        ||:
  Rat    77 VSSVPRPE-----------GHSRPQVMDTEHSNLPDSGSSG--------PPD------------- 109

  Fly   452 LPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGG 516
                            |.:|..      |..:..|.||...|...||...             ||
  Rat   110 ----------------PAWGSE------RRGEESSGQFLVAGTGTAAGGG-------------GG 139

  Fly   517 VVSGS----GEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQ-----QQQQAVQQQQQQGAQQQ 572
            ::..|    ..|.||.|:.:...    ||...|||.:.|....     ::.:.:||:|
  Rat   140 LILASPKLGATPLPPESTPAPPP----PPPPPPPPGVGSGHLNIPLILEELRVLQQRQ------- 193

  Fly   573 LQSAQQQQQSQQQSQQQQQI-----------TPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTS 626
               ..|.|.::|..:|...:           :|..:.|.|.:...:|....|...:..|...|.:
  Rat   194 ---IHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPAQTGKTLA 255

  Fly   627 PGAGSTVNSSSPSPRQ----------KQSP---------HFASPSPSQQ---QQQQLATIPRPHS 669
            ..:.|:.:|.:..|:|          .|.|         |..:|:||..   ...||  |..||
  Rat   256 SSSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQL--IASPH- 317

  Fly   670 LTPPEKLGDASSE--NGSLGLILASTPRSASTPPSKTGDV-------SLQEPIAHCYSCSYCDKK 725
            |..|...|..:::  ..:.||..|::| ....|.:.:|::       ||::|... :.|.:|.|.
  Rat   318 LAFPGTTGLLAAQCLGAARGLEAAASP-GLLKPKNGSGELGYGEVISSLEKPGGR-HKCRFCAKV 380

  Fly   726 FRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHR--------SPADDQDNQDNQDD 782
            |..::.|.||.|:||||:||||..|....:....|..|...||        :|....::.|.
  Rat   381 FGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDY--- 442

  Fly   783 GSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSV 847
                 .:.::.........|:::|||..    .|.|                    ..:.:.|..
  Rat   443 -----VITSSGLPYGMSVPPEKAEEEAA----TPGG--------------------GVERKPLVA 478

  Fly   848 SNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAAD 912
            |......::|....|:|.::.|...:..|....:.:..|. |..:.|:....:..:|.:..|.:.
  Rat   479 STTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVEP-KSKVDENTPPGSEGSAISGVADSG 542

  Fly   913 NNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFP--------NP 969
            :..|    ..||..:..||..|  |.....|:...|                |||        :|
  Rat   543 SATR----MQLSKLVTSLPSWA--LLTNHLKSTGSF----------------PFPYVLEPLGASP 585

  Fly   970 FELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCG 1034
            .|.||..:        :.:.:.|..|    :.:.....|...:....|   ..|....:.|..|.
  Rat   586 SETSKLQQ--------LVEKIDRQGA----VAVASTASGAPTTSAPAP---SSSASGPNQCVICL 635

  Fly  1035 KVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTH--GRTGKDVYRCRFCDMPFSV 1097
            :|......|.:|...|.||:|:||::|..|.:....|..|...|  ....:....|..|...|:.
  Rat   636 RVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTN 700

  Fly  1098 PSTLEKHMRK----CVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQS 1158
            ..||::|:|.    .:.|.|........||...:::.:......:..|.||.|..|.:..:.::.
  Rat   701 AVTLQQHVRMHLGGQIPNGGSTLPEGGGVAQENSSEQSTASGPGSFPQPQAQQPSAEEEISEEEE 765

  Fly  1159 QQQQQQLSPMGVVGYPPQFVSGHNLSLPG-----------SVSGDND----SNASSSMTGVHPIS 1208
            :.::::           :.|:..: ||.|           ||.||::    :...::.:|..|.:
  Rat   766 EDEEEE-----------EDVTDED-SLAGRGSESGGEKAISVRGDSEEVSGAEEEAATSGAAPTN 818

  Fly  1209 LKE----EAXLFSGFPVPLAPPPPLQQHQPHLQQPQQQQTS 1245
            .||    |.......|.|  ||||....:|   ||.:|..|
  Rat   819 GKEVDNNEKATQQALPPP--PPPPDNLDRP---QPMEQGPS 854

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9650	NP_001356899.1	zf-C2H2	717..739	CDD:333835	8/21 (38%)
		C2H2 Zn finger	719..739	CDD:275368	8/19 (42%)
		zf-H2C2_2	731..756	CDD:338759	13/24 (54%)
		C2H2 Zn finger	747..767	CDD:275368	4/19 (21%)
		zf-C2H2	1029..1050	CDD:333835	5/20 (25%)
		C2H2 Zn finger	1030..1050	CDD:275368	5/19 (26%)
		zf-H2C2_2	1042..1067	CDD:338759	10/24 (42%)
		C2H2 Zn finger	1058..1078	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1088..1106	CDD:275368	6/17 (35%)
Sall2	NP_001100732.1	C2H2 Zn finger	374..394	CDD:275368	8/19 (42%)
		zf-H2C2_2	386..411	CDD:290200	13/24 (54%)
		C2H2 Zn finger	402..422	CDD:275368	4/19 (21%)
		C2H2 Zn finger	631..651	CDD:275368	5/19 (26%)
		zf-H2C2_2	643..668	CDD:290200	10/24 (42%)
		C2H2 Zn finger	659..679	CDD:275368	5/19 (26%)
		zf-C2H2	690..711	CDD:278523	7/20 (35%)
		C2H2 Zn finger	691..711	CDD:275368	7/19 (37%)
		C2H2 Zn finger	910..930	CDD:275368
		zf-C2H2	910..930	CDD:278523
		C2H2 Zn finger	939..957	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340118
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930