DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9650 and Zfp287

DIOPT Version :9

Sequence 1:	NP_001356899.1	Gene:	CG9650 / 31660	FlyBaseID:	FBgn0029939	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	NP_001100478.1	Gene:	Zfp287 / 303212	RGDID:	1308617	Length:	762	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	97/429 - (22%)
Similarity:	140/429 - (32%)	Gaps:	132/429 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   717 YSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQD 781
            |.|:.|.|.|....:|.||||||||||||||..|....||...|:.|.|||........|:..:.
  Rat   450 YKCNDCGKDFSQRAHLTIHQRTHTGEKPYKCLECSKTFSHSSSLINHQRVHTGEKPYICNECGKT 514

  Fly   782 DGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLS 846
            ...:...|:..:....:.|.                             :..||..:..::..|.
  Rat   515 FSQSTHLLQHQKIHTGKKPY-----------------------------KCNECWKVFSQSTYLI 550

  Fly   847 VSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAA 911
            ...||....:..|.|..|..              .|..|...:.....:|.|.........|
  Rat   551 RHQRIHSGEKCYKCTECGKA--------------FAHSSTLIQHQTTHTGEKSYICNVCGKA--- 598

  Fly   912 DNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQ--QPQDGGAPSQVPLF-NPFPNPFELS 973
                                         |:::.|:.|  :...|..|.:..:. ..|.....|:
  Rat   599 -----------------------------FSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLT 634

  Fly   974 KRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFK 1038
            :.            |.:|..|..|:                               |..|||.::
  Rat   635 QH------------QRIHNGEKPFK-------------------------------CNTCGKAYR 656

  Fly  1039 NCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEK 1103
            ..:|||.|:|.|||||||||..|..|...||.|.:|.:||  ||:..|:|..|:..||..:.|.:
  Rat   657 QGANLTQHQRVHTGEKPYKCHHCGKAFIYSSSLNQHRRTH--TGERPYKCTHCNKDFSQRTCLIQ 719

  Fly  1104 HMR--------KCVVNQGKAAAAANAVAAAQAAQAAAQH 1134
            |.|        .|.: .||:...:..:...|.....|:|
  Rat   720 HQRIHTGERPYGCRI-CGKSFTQSTNLIQHQRVHMGARH 757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9650	NP_001356899.1	zf-C2H2	717..739	CDD:333835	10/21 (48%)
		C2H2 Zn finger	719..739	CDD:275368	9/19 (47%)
		zf-H2C2_2	731..756	CDD:338759	16/24 (67%)
		C2H2 Zn finger	747..767	CDD:275368	7/19 (37%)
		zf-C2H2	1029..1050	CDD:333835	9/20 (45%)
		C2H2 Zn finger	1030..1050	CDD:275368	9/19 (47%)
		zf-H2C2_2	1042..1067	CDD:338759	16/24 (67%)
		C2H2 Zn finger	1058..1078	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1088..1106	CDD:275368	6/17 (35%)
Zfp287	NP_001100478.1	SCAN	46..133	CDD:280241
		KRAB	168..225	CDD:214630
		KRAB	168..207	CDD:279668
		C2H2 Zn finger	368..388	CDD:275368
		zf-C2H2	394..416	CDD:278523
		C2H2 Zn finger	396..416	CDD:275368
		zf-H2C2_2	408..433	CDD:290200
		COG5048	420..752	CDD:227381	95/422 (23%)
		C2H2 Zn finger	424..444	CDD:275368
		zf-H2C2_2	436..461	CDD:290200	5/10 (50%)
		C2H2 Zn finger	452..472	CDD:275368	9/19 (47%)
		zf-H2C2_2	464..489	CDD:290200	16/24 (67%)
		C2H2 Zn finger	480..500	CDD:275368	7/19 (37%)
		zf-H2C2_2	492..517	CDD:290200	6/24 (25%)
		C2H2 Zn finger	508..528	CDD:275368	2/19 (11%)
		zf-H2C2_2	520..545	CDD:290200	4/53 (8%)
		C2H2 Zn finger	536..556	CDD:275368	4/19 (21%)
		zf-H2C2_2	548..573	CDD:290200	6/38 (16%)
		C2H2 Zn finger	564..584	CDD:275368	4/33 (12%)
		zf-C2H2	590..612	CDD:278523	4/53 (8%)
		C2H2 Zn finger	592..612	CDD:275368	4/51 (8%)
		zf-H2C2_2	604..629	CDD:290200	5/24 (21%)
		C2H2 Zn finger	620..640	CDD:275368	3/31 (10%)
		zf-H2C2_2	632..657	CDD:290200	9/67 (13%)
		C2H2 Zn finger	648..668	CDD:275368	9/19 (47%)
		zf-H2C2_2	660..685	CDD:290200	16/24 (67%)
		C2H2 Zn finger	676..696	CDD:275368	7/19 (37%)
		zf-H2C2_2	688..713	CDD:290200	10/26 (38%)
		C2H2 Zn finger	704..724	CDD:275368	7/19 (37%)
		zf-H2C2_2	717..741	CDD:290200	6/24 (25%)
		C2H2 Zn finger	732..752	CDD:275368	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000