DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9650 and Zfp958

DIOPT Version :9

Sequence 1:	NP_001356899.1	Gene:	CG9650 / 31660	FlyBaseID:	FBgn0029939	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	XP_038944925.1	Gene:	Zfp958 / 100302405	RGDID:	2311392	Length:	495	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	116/487 - (23%)
Similarity:	173/487 - (35%)	Gaps:	126/487 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   647 HFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQE 711
            ||.| |....:.::..|..:|:.   ..|.|:|.:...||          .:...:.||    ::
  Rat    55 HFQS-SRRHGRPERSHTEEKPYE---DMKCGEAFAHRSSL----------RAHERTHTG----EK 101

  Fly   712 PIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDN 776
            |    |.|:.|||.|.:.::|.||:|||||||.|||..|....|....|.:|.|.|......:.|
  Rat   102 P----YGCNQCDKAFAYHSSLRIHERTHTGEKLYKCIQCGKAFSDQNTLQRHKRTHSEEKPCKCN 162

  Fly   777 QDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYK 841
            |..:....:: ||..:|..:       ..|:..|                        |...| |
  Rat   163 QCGKAFAHHS-SLRKHERTH-------TGEKPYG------------------------CNQCD-K 194

  Fly   842 AEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAA 906
            |.....|.|      ..:.|.:|.........||    ..|.:|...|.....:|.|........
  Rat   195 AFACHSSLR------RHERTHTGEKPYECNQCDK----AFAYHSSLQKHERTHTGEKPYGCNQCD 249

  Fly   907 AAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNM--FQQPQDGGAPSQVPLFNPFPNP 969
            .|.|..::.|........:|    |....:....||.:..:  .::...|..|.:.   |.....
  Rat   250 KAFACHSSLRKHERTHTGEK----PYECNQCGKAFACHSTLRKHERIHTGEKPYEC---NQCGKA 307

  Fly   970 FELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCG 1034
            |.:...::        :.:..|..|..||                               |..||
  Rat   308 FSMQNTLR--------VHERTHTGEKPFE-------------------------------CNQCG 333

  Fly  1035 KVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPS 1099
            |.||..|.|.:|:|.||||||::|:.|....|..|...:|.:.|  :|:..|.|..||..|::.|
  Rat   334 KTFKLHSQLRIHKRVHTGEKPHECDQCGKTFACPSSFQKHKRVH--SGEKPYGCNQCDKAFAIHS 396

  Fly  1100 TLEKHMR--------KCVVNQ-GKAAAAANAV 1122
            .|.||.|        ||  || ||..:.:|::
  Rat   397 RLRKHERTHTGEKPFKC--NQCGKTFSQSNSL 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9650	NP_001356899.1	zf-C2H2	717..739	CDD:333835	10/21 (48%)
		C2H2 Zn finger	719..739	CDD:275368	9/19 (47%)
		zf-H2C2_2	731..756	CDD:338759	14/24 (58%)
		C2H2 Zn finger	747..767	CDD:275368	6/19 (32%)
		zf-C2H2	1029..1050	CDD:333835	10/20 (50%)
		C2H2 Zn finger	1030..1050	CDD:275368	10/19 (53%)
		zf-H2C2_2	1042..1067	CDD:338759	11/24 (46%)
		C2H2 Zn finger	1058..1078	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1088..1106	CDD:275368	8/17 (47%)
Zfp958	XP_038944925.1	KRAB	4..44	CDD:396083
		C2H2 Zn finger	80..97	CDD:275368	4/26 (15%)
		C2H2 Zn finger	105..125	CDD:275368	9/19 (47%)
		COG5048	129..490	CDD:227381	87/391 (22%)
		C2H2 Zn finger	133..153	CDD:275368	6/19 (32%)
		C2H2 Zn finger	161..181	CDD:275368	5/20 (25%)
		C2H2 Zn finger	189..209	CDD:275368	6/26 (23%)
		C2H2 Zn finger	217..237	CDD:275368	5/23 (22%)
		C2H2 Zn finger	245..265	CDD:275368	3/19 (16%)
		C2H2 Zn finger	273..293	CDD:275368	2/19 (11%)
		C2H2 Zn finger	301..321	CDD:275368	2/30 (7%)
		C2H2 Zn finger	329..349	CDD:275368	10/19 (53%)
		C2H2 Zn finger	357..377	CDD:275368	5/19 (26%)
		C2H2 Zn finger	385..405	CDD:275368	9/19 (47%)
		C2H2 Zn finger	413..433	CDD:275368	6/16 (38%)
		C2H2 Zn finger	441..461	CDD:275368
		C2H2 Zn finger	469..489	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000