Sequence 1: | NP_511068.2 | Gene: | fz4 / 31659 | FlyBaseID: | FBgn0027342 | Length: | 705 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_059108.1 | Gene: | FZD3 / 7976 | HGNCID: | 4041 | Length: | 666 | Species: | Homo sapiens |
Alignment Length: | 721 | Identity: | 175/721 - (24%) |
---|---|---|---|
Similarity: | 280/721 - (38%) | Gaps: | 166/721 - (23%) |
- Green bases have known domain annotations that are detailed below.
Fly 46 CETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPK 110
Fly 111 APVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQD 175
Fly 176 LYGLPGQGIPGGL----GGKLPMDCS---GLAKSHLYVRLPRSGRCAPLCEADILFTPAEKHLAE 233
Fly 234 IWVSTWAYAALGLALVATVCLLAS---------DGSRLASAKWSRLLSPLIW---CHNMVTLGWA 286
Fly 287 VRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAACAWWAVLCLGWHRDIRR 351
Fly 352 HSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNFVCFVAWGLPAFQTSAVIVARFVDADELL 416
Fly 417 GACFVGNQSDKALQILVATPVFCYWIFGSMNLISGYLVHCRTK-EI-LRNSNALSVQQQLQQLSA 479
Fly 480 HSSSGIGIFLFIYGLACAMLLLAVIYEFANIDVWLGSGDT----------------------NTP 522
Fly 523 LWPFLLRAFMELMLGI----------CCFAW-----------VLGPSISTLYKRQVSNGKM---- 562
Fly 563 --VKHTSAGAATGHLDGHSSS---------RGSHAACNSTVVSYH-SVRTSMASVPLPPSPYKLK 615
Fly 616 TSPGTGSISLNQMSNYSLGRSVHHQQRHSPHHHHHQQQQHHQFHPHHN----HQHHSTSSHRLYY 676
Fly 677 PPGSYA 682 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fz4 | NP_511068.2 | CRD_FZ4 | 43..169 | CDD:143557 | 43/122 (35%) |
7tm_4 | 223..544 | CDD:304433 | 81/377 (21%) | ||
FZD3 | NP_059108.1 | CRD_FZ3 | 24..150 | CDD:143558 | 45/134 (34%) |
7tmF_FZD3 | 192..512 | CDD:320161 | 81/371 (22%) | ||
TM helix 1 | 201..226 | CDD:320161 | 5/34 (15%) | ||
TM helix 2 | 235..256 | CDD:320161 | 6/25 (24%) | ||
TM helix 3 | 287..313 | CDD:320161 | 9/25 (36%) | ||
TM helix 4 | 330..352 | CDD:320161 | 5/31 (16%) | ||
TM helix 5 | 366..391 | CDD:320161 | 6/24 (25%) | ||
TM helix 6 | 419..444 | CDD:320161 | 6/28 (21%) | ||
TM helix 7 | 473..498 | CDD:320161 | 7/24 (29%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 502..507 | 2/4 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 538..666 | 33/138 (24%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |