DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and szl

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001037971.1	Gene:	szl / 733750	XenbaseID:	XB-GENE-482077	Length:	281	Species:	Xenopus tropicalis

Alignment Length:	146	Identity:	50/146 - (34%)
Similarity:	76/146 - (52%)	Gaps:	16/146 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QCETI--RIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMC 107
            :|.:|  .:.||..|||:|..:|||:|:....:|......:..|::..|....::|||:.:.|:|
Frog    26 KCVSIPKEMAMCNDIGYSEMRLPNLMGHTSMAEVVPKSAEWQNLLQTGCHPYARMFLCSLFAPVC 90

  Fly   108 TPKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQ 172
            ...    .|.||||:|.:||..|.|||...|..||.:||||:||.   .|.||::...:.:|...
Frog    91 LDT----FIQPCRSMCVAVRDSCAPVLACHGHAWPESLDCDRFPA---GEDMCLDTLSKEYQYSY 148

  Fly   173 EQDLYGLPG---QGIP 185
            ::    ||.   ||.|
Frog   149 KE----LPKPSCQGCP 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	44/125 (35%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
szl	NP_001037971.1	CRD_sizzled	19..159	CDD:143561	48/143 (34%)
szl	NP_001037971.1	NTR_Sfrp1_like	153..281	CDD:239635	3/8 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910