| Sequence 1: | NP_511068.2 | Gene: | fz4 / 31659 | FlyBaseID: | FBgn0027342 | Length: | 705 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_742032.2 | Gene: | Fzd2 / 64512 | RGDID: | 71012 | Length: | 570 | Species: | Rattus norvegicus |
| Alignment Length: | 589 | Identity: | 162/589 - (27%) |
|---|---|---|---|
| Similarity: | 251/589 - (42%) | Gaps: | 112/589 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 9 LLVVILLHPRISKSSTSGNPSASSSSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPNLVGNEMQ 73
Fly 74 TDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQGFG 138
Fly 139 FPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQDLY------GL-PGQ-GIPGGLGG----- 190
Fly 191 -----KLPMDCSGLAK--SHLYVRLPRSGRCAPLCE-----ADILFTPAEKHLAEIWVSTWAYAA 243
Fly 244 LGLALVATVCLLASDGSRLASAKWSRLLSPLIW---CHNMVTLGWAVRFMVGRTGTACGTDPQAP 305
Fly 306 NESL------LTVDGLSNASCASVFLMRYYFGMAACAWWAVLCLGWHRDIRRHSPDSK-GHVVIP 363
Fly 364 SNFGGSPAKRNSAKTAQQDLTQNNFVCFVAWGLPAFQTSAVIVARFVDADELLGACFVGNQSDKA 428
Fly 429 LQILVATPVFCYWIFGSMNLISGYLVHCRTKEILRNSNALSVQQQLQQLSAHSSSGIGIFLFIYG 493
Fly 494 LACAMLLLAVIYEFANIDVWLGSGDTN-------------TP-LWP----FLLRAFMELMLGICC 540
Fly 541 FAWV 544 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz4 | NP_511068.2 | CRD_FZ4 | 43..169 | CDD:143557 | 51/125 (41%) |
| 7tm_4 | 223..544 | CDD:304433 | 80/348 (23%) | ||
| Fzd2 | NP_742032.2 | CRD_FZ2 | 40..166 | CDD:143573 | 52/131 (40%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 166..194 | 11/27 (41%) | |||
| 7tmF_FZD2 | 239..568 | CDD:320373 | 81/351 (23%) | ||
| TM helix 1 | 249..273 | CDD:320373 | 6/24 (25%) | ||
| TM helix 2 | 282..303 | CDD:320373 | 5/25 (20%) | ||
| TM helix 3 | 333..355 | CDD:320373 | 9/21 (43%) | ||
| TM helix 4 | 376..392 | CDD:320373 | 5/15 (33%) | ||
| TM helix 5 | 414..437 | CDD:320373 | 6/22 (27%) | ||
| TM helix 6 | 468..490 | CDD:320373 | 5/21 (24%) | ||
| TM helix 7 | 519..544 | CDD:320373 | 5/24 (21%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 548..553 | ||||
| PDZ-binding | 568..570 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||