DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and col18a1a

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_021334395.1	Gene:	col18a1a / 564123	ZFINID:	ZDB-GENE-030516-3	Length:	1645	Species:	Danio rerio

Alignment Length:	149	Identity:	36/149 - (24%)
Similarity:	57/149 - (38%)	Gaps:	16/149 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SKSSTSGNPSASSSSSSPPEIPAFRQCETIR-------IEMCRKIGYNETSMPNLVGNEMQTDVE 77
            |:.:.|.|.....|......:||  ..|.:|       :..|.:.|....|:||.:......:|.
Zfish   178 SEYAVSDNALTIESQFLIASMPA--SFEPLRCLPVDSGLPFCTRRGVESFSVPNFLNQSSVEEVR 240

  Fly    78 YTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWP 142
            ..|..:|.|:...|...|:.|.|....|.|....   ::.||||.||.::..|..:|.....|
Zfish   241 MVLTEWAWLLRSGCHHSLEWFFCLLLTPRCGHSG---SLLPCRSSCEVLQDSCWTLLDEGRLP-- 300

  Fly   143 PALDCDKFPRENNHETMCM 161
              ::|...|.|.:....|:
Zfish   301 --VECKSLPEEKHDGYRCL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	30/126 (24%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
col18a1a	XP_021334395.1	CRD_Collagen_XVIII	203..340	CDD:143564	30/122 (25%)
		LamG	327..516	CDD:328935
		Collagen	816..860	CDD:189968
		Collagen	<937..980	CDD:189968
		Collagen	959..1055	CDD:189968
		Endostatin	1471..1639	CDD:310825
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810