DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and frzb

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001005438.1	Gene:	frzb / 448021	XenbaseID:	XB-GENE-481353	Length:	319	Species:	Xenopus tropicalis

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	80/177 - (45%)	Gaps:	28/177 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPK 110
            ||.:||.||:.:.:|.|.|||.:.:..|.:....::.|..|:..:||..|..||||.|.|:||..
Frog    31 CEPVRIPMCKSMPWNMTKMPNHLHHSTQANAILAIEQFEGLLTTECSQDLLFFLCAMYAPICTID 95

  Fly   111 APVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQD 175
            .....|.||:|:||..|..|.|:|..:...||.:|.|::.|..:  ..:|: .|..:...:|..|
Frog    96 FQHEPIKPCKSVCERARAGCEPILIKYRHTWPESLACEELPVYD--RGVCI-SPEAIITVEQGTD 157

  Fly   176 LYGLPGQGIPGGLGGKLPMD-----CSGLAKSHLYVRLPRSGRCAPL 217
              .:|          ..|||     |...|..|.        :|.|:
Frog   158 --SMP----------DFPMDSNNGNCGSTAGEHC--------KCKPM 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	42/122 (34%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
frzb	NP_001005438.1	CRD_SFRP3	28..153	CDD:143550	42/124 (34%)
frzb	NP_001005438.1	NTR_Sfrp3_like	189..299	CDD:239636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910