DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and sfrp2

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_989062.1	Gene:	sfrp2 / 394659	XenbaseID:	XB-GENE-485147	Length:	295	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	55/158 - (34%)
Similarity:	81/158 - (51%)	Gaps:	15/158 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CLLVVILLHPRISKSSTS----GNPSASSSSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPNLV 68
            |||:::||......|...    |.|..|...|:...|||       .:.:|..|.|....:|||:
Frog     7 CLLLLVLLASDCMDSVRGLFPFGQPEFSYKRSNCKPIPA-------TLVLCHDIEYPNMRLPNLL 64

  Fly    69 GNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPV 133
            |:|...:|.....::.||::..|....|.|||:.:.|:|..... ..|.|||||||.|:..|.||
Frog    65 GHETMKEVLQQASSWIPLVQKQCHQDTKKFLCSLFAPVCIDDLD-ETIKPCRSLCEQVKDSCAPV 128

  Fly   134 LQGFGFPWPPALDCDKFPRENNHETMCM 161
            :..||||||..|:|.:||::|:   :|:
Frog   129 MSAFGFPWPDMLECSRFPQDND---LCI 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	42/119 (35%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
sfrp2	NP_989062.1	CRD_SFRP2	36..163	CDD:143555	46/129 (36%)
sfrp2	NP_989062.1	NTR_Sfrp1_like	169..295	CDD:239635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910