DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fz4 and frzb

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_571018.1	Gene:	frzb / 30119	ZFINID:	ZDB-GENE-990715-1	Length:	315	Species:	Danio rerio

Alignment Length:	210	Identity:	63/210 - (30%)
Similarity:	91/210 - (43%)	Gaps:	52/210 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CIL---CLLVVILLHPRISKSSTSGNPSASSSSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPN 66
            |:|   |||.:    ||       |..:||              ||.|||.||:.:.:|.|.|||
Zfish    12 CVLAFACLLEI----PR-------GTGAAS--------------CEPIRIPMCKSMPWNMTKMPN 51

  Fly    67 LVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCH 131
            .:.:..|.:....::.|..|:...||:.|..||||.|.|:||.......|.||:|:||..:..|.
Zfish    52 HLHHSTQANAVLAIEQFEGLLGTQCSADLLFFLCAMYAPICTIDFQHDPIKPCKSVCERAKCGCE 116

  Fly   132 PVLQGFGFPWPPALDCDKFPRENNHETMCM--------EGPGELHQPQQEQDLYGLPGQGIPGGL 188
            ||::.:...||.:|.|::.|..:  ..:|:        |||        :...|..|.:..|.|
Zfish   117 PVMKRYNHTWPESLACEELPVYD--RGVCISPEAIVKAEGP--------DNSYYQDPAKCNPEG- 170

  Fly   189 GGKLPMD-----CSG 198
            ....|||     |.|
Zfish   171 NPDFPMDSHNTNCKG 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	44/133 (33%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
frzb	NP_571018.1	CRD_SFRP3	28..153	CDD:143550	43/140 (31%)
frzb	NP_571018.1	NTR_Sfrp3_like	200..310	CDD:239636
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810