DRSC/TRiP Functional Genomics Resources

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Protein Alignment fz4 and FRZB

DIOPT Version :9

Sequence 1:NP_511068.2 Gene:fz4 / 31659 FlyBaseID:FBgn0027342 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_001454.2 Gene:FRZB / 2487 HGNCID:3959 Length:325 Species:Homo sapiens


Alignment Length:216 Identity:56/216 - (25%)
Similarity:84/216 - (38%) Gaps:59/216 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LCLLVVILLHPRISKSSTSGNPSASSSSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPNLVGNE 71
            ||||.|               |.|.:::           ||.:||.:|:.:.:|.|.|||.:.:.
Human    22 LCLLRV---------------PGARAAA-----------CEPVRIPLCKSLPWNMTKMPNHLHHS 60

  Fly    72 MQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQG 136
            .|.:....::.|..|:...||..|..||||.|.|:||.......|.||:|:||..|..|.|:|..
Human    61 TQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIK 125

  Fly   137 FGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQDLYGLPGQGIPGGLGGKLPMD-----C 196
            :...||..|.|::.|..:  ..:|                  :..:.|....|...|||     |
Human   126 YRHSWPENLACEELPVYD--RGVC------------------ISPEAIVTADGADFPMDSSNGNC 170

  Fly   197 SGLAKSHLYVRLPRSGRCAPL 217
            .|.:....        :|.|:
Human   171 RGASSERC--------KCKPI 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fz4NP_511068.2 CRD_FZ4 43..169 CDD:143557 40/125 (32%)
7tm_4 223..544 CDD:304433
FRZBNP_001454.2 CRD_SFRP3 32..157 CDD:143550 41/155 (26%)
NTR_Sfrp3_like 188..297 CDD:239636
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 297..325
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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