DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and Frzb

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_035486.1	Gene:	Frzb / 20378	MGIID:	892032	Length:	323	Species:	Mus musculus

Alignment Length:	216	Identity:	57/216 - (26%)
Similarity:	85/216 - (39%)	Gaps:	59/216 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LCLLVVILLHPRISKSSTSGNPSASSSSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPNLVGNE 71
            ||||.|               |.|.:::           ||.:||.:|:.:.:|.|.|||.:.:.
Mouse    22 LCLLQV---------------PGAQAAA-----------CEPVRIPLCKSLPWNMTKMPNHLHHS 60

  Fly    72 MQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQG 136
            .|.:....::.|..|:...||..|..||||.|.|:||.......|.||:|:||..|..|.|:|..
Mouse    61 TQANAILAMEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIK 125

  Fly   137 FGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQDLYGLPGQGIPGGLGGKLPMD-----C 196
            :...||.:|.||:.|..:  ..:|                  :..:.|....|...|||     |
Mouse   126 YRHSWPESLACDELPVYD--RGVC------------------ISPEAIVTADGADFPMDSSTGHC 170

  Fly   197 SGLAKSHLYVRLPRSGRCAPL 217
            .|.:....        :|.|:
Mouse   171 RGASSERC--------KCKPV 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	41/125 (33%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
Frzb	NP_035486.1	CRD_SFRP3	32..157	CDD:143550	42/155 (27%)
		NTR_Sfrp3_like	188..297	CDD:239636
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810