Protein Alignment fz4 and cfz-2

DIOPT Version :9

• Sequence 1: NP_511068.2
• Gene: fz4 / 31659
• FlyBaseID: FBgn0027342
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_503965.2
• Gene: cfz-2 / 178768
• WormBaseID: WBGene00000478
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 165/591 - (27%)
• Similarity: 247/591 - (41%)
• Gaps: 109/591 - (18%)

  Fly    44 RQCETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCT 108
            ::||.|.|.:|:.||||.||.||..|:|.|.:....:..|.||:|..|...||.|||..|.|:|.
 Worm    23 QKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQ 87

  Fly   109 PKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHET---MCMEGP------ 164
            .... ..|.||..||...|.:|.|::..:||.||..|.|:..|:.::..:   :|...|
 Worm    88 ENYD-KPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQ 151

  Fly   165 --GELH--QPQQEQDLYGLPGQGIPGGLGGKL-------PMDCSGLAKSHL-YVRLPRS-----G 212
              |..|  |.|.:...:.....|...|: .|:       |.:|........ :|...:|     .
 Worm   152 HKGHHHKNQNQNQNQNHNYSPDGPEVGI-SKIDNEVIAGPSECQCTCNQPFQFVASEKSKVGNVT 215

  Fly   213 RCAPLCEADILFTPAEKH-LAEIWVSTWAYAALGLALVATVCLLASDGSRLASAKWSRLLSP--- 273
            .||..|.:..|   ||.| |...|::.|:         .|.|:|||........:..|...|
 Worm   216 NCAYSCHSPAL---AESHSLVSNWMAFWS---------ITCCVLASFTFLTFLIETDRFQYPERP 268

  Fly   274 ---LIWCHNMVTLGWAVRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAAC 335
               |.:|..||.:|:.:|:.||....||      .:..:...|..|.:.|..|||:.|:|||||.
 Worm   269 IFMLAFCQLMVAVGFMIRYFVGHEEIAC------DSMRIKGADDNSGSLCFVVFLLTYFFGMAAS 327

  Fly   336 AWWAVLCLGWHRDIRRHSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNF-VCFVAWGLPAF 399
            .||.:|.|.|               |:.:          ::|.:.:.::..:| ...|.|.|||.
 Worm   328 VWWVILSLTW---------------VLSA----------ASKWSPEAISSFSFHFHVVGWCLPAI 367

  Fly   400 QTSAVIVARFVDADELLGACFVGNQSDKALQILVATPVFCYWIFGSMNLISGYLVHCRTKEILRN 464
            ||..|||...:|.|.:.|.|:|||...:..:|.|..|:..|:|.|.:.|:.|:   |....| ||
 Worm   368 QTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGF---CNLWSI-RN 428

  Fly   465 SNALSVQQQLQQL-SAHS----SSGIGIFLFIYGLACAMLLLAVIYEFANIDVWLGS-------- 516
                .||:|...| |||.    .|.||||..:|.:...:::..:.||..:..:|..|
 Worm   429 ----EVQKQHPSLESAHKITQLMSKIGIFSLLYTIPSLLIICVLFYEQNHRSLWEQSQLCSCSPK 489

  Fly   517 ---GDTNTPLWPFLLRAFMELMLGICCFAWVLGPSISTLYKRQV----SNGKMVKHTSAGAATGH 574
               ||::  |...|::.....:||.....||......:.:|..:    |:..:.|:..|......
 Worm   490 QTIGDSS--LIISLIKTCCMCILGWTSGFWVCSTKTLSSWKNAICCLGSSRSLPKYQPADILYAK 552

  Fly   575 LDGHSS 580
            .|..||
 Worm   553 SDMSSS 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	48/137 (35%)
		7tm_4	223..544	CDD:304433	96/344 (28%)
cfz-2	NP_503965.2	CRD_FZ5_like	24..146	CDD:143565	45/122 (37%)
		Frizzled	230..532	CDD:279827	96/351 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D237456at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920