Protein Alignment fz4 and mig-1

DIOPT Version :9

• Sequence 1: NP_511068.2
• Gene: fz4 / 31659
• FlyBaseID: FBgn0027342
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_001021744.1
• Gene: mig-1 / 171677
• WormBaseID: WBGene00003238
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 160/643 - (24%)
• Similarity: 245/643 - (38%)
• Gaps: 196/643 - (30%)

  Fly    44 RQCETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCT 108
            ::|:.:..|||..:.||.||.||||..|...|...::.|:.||:...||.|||.|||:.|.|||.
 Worm    24 QRCQKVDHEMCNDLPYNLTSFPNLVDEESWKDASESILTYKPLLSVVCSEQLKFFLCSVYFPMCN 88

  Fly   109 PKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQE 173
            .|. .:.|||||.||.||:.:|.|||:.|||.||..:.|||||.|||.|.|||:||.|....|.|
 Worm    89 EKL-ANPIGPCRPLCLSVQEKCLPVLESFGFKWPDVIRCDKFPLENNREKMCMKGPNEQGAIQDE 152

  Fly   174 QDLYGLPGQGIPGG------------LGGKLPMDCSGLAKSHLYVRLPRSGRCAPLC-------E 219
            :..:........|.            |.||.|.|         .|.|.||.:|.|||       :
 Worm   153 RAKFAAKESEDDGNDRVEDIQREVDRLNGKCPQD---------EVFLNRSSKCVPLCSNPQKVGQ 208

  Fly   220 AD-------ILFTPAEKHLAEIWVSTWAYAALGLALVATVCLLASDGSRL----ASAKWSRLLSP 273
            .|       :||.    .|:.:.::..:...:||::..         .||    :..:.:...|.
 Worm   209 TDRESATRLLLFL----SLSSVILTILSVFIVGLSIYF---------RRLEMLHSLTETAMFFSC 260

  Fly   274 LIWCHN----MVTLGWAVRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAA 334
            :.:|..    :|::.:..:|.:..|        ...:..|..|.|||:..|:||..:.||....:
 Worm   261 ISFCATSVIYIVSISFKDQFQISCT--------DYTHHLLFVVGGLSHVPCSSVASLIYYTATCS 317

  Fly   335 CAWWAVLCLGWHRDIRRHSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNFVCFVAWGLPAF 399
            ..||.::|:.|::..|      ..|::            :.::|.         |..:..|:|..
 Worm   318 RLWWLLICVSWNKATR------TSHIL------------DDSRTR---------VIMLILGIPLA 355

  Fly   400 QTSAVIVARFVDADELLGACFVGNQSDKALQILVATPVFCYWIFGSMNLISGYLVHCRTKEILRN 464
            .....::|:.|.|:.|.|.||:|          .|:| ...|||.....:..:|:         :
 Worm   356 PLMLALLAKAVAANPLTGLCFIG----------AASP-GTDWIFNFCRELILFLI---------S 400

  Fly   465 SNALSVQQQLQQLSAHSSSGIGIFLFIYGLACAMLL-------------LAVIYEFANIDVWLGS 516
            |.|||                        .||..||             :|.:|..|.:...|..
 Worm   401 SIALS------------------------SACCRLLGSDEQDVNGFAGVIAAVYPIAGLFYMLSF 441

  Fly   517 GDTNTPLWPFLL--RAF---------MELMLGICCFAWVLGPSISTLYKRQVSNGKMVKHTSAGA 570
              .|....|||.  |:|         .:|:|.....|:.|   |..|:|...|:.|
 Worm   442 --VNDATQPFLSLDRSFNAVSATKFSFDLLLSFIMCAFCL---IYLLFKLTRSSSK--------- 492

  Fly   571 ATGHLDGHSSSRGSHAACNSTVVSYHSVRTSMASVPLPPSPYKLKTSPGTGSISLNQM 628
                                  ||....:.::..:|.|..|..::::....:...|.|
 Worm   493 ----------------------VSKEGYQPAVPKLPQPAIPGSVRSNTYASTFRTNNM 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	63/124 (51%)
		7tm_4	223..544	CDD:304433	67/352 (19%)
mig-1	NP_001021744.1	CRD_FZ	23..148	CDD:295308	63/124 (51%)
		7tm_4	257..>328	CDD:304433	18/78 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I3591
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5843
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109675
Panther	1	1.100	-	-	LDO	PTHR11309
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860