| Sequence 1: | NP_511068.2 | Gene: | fz4 / 31659 | FlyBaseID: | FBgn0027342 | Length: | 705 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001155966.1 | Gene: | Fzd6 / 14368 | MGIID: | 108474 | Length: | 709 | Species: | Mus musculus |
| Alignment Length: | 665 | Identity: | 155/665 - (23%) |
|---|---|---|---|
| Similarity: | 259/665 - (38%) | Gaps: | 160/665 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 46 CETIRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPK 110
Fly 111 APVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGELHQPQQEQD 175
Fly 176 LYGLPGQGIPGGLGGKLPMDCSGLAKSHLYVRLPRSG----------RCAPLCEADILFTPAEKH 230
Fly 231 LAEIWVSTWAYAALGLALVATVCLLAS---------DGSRLASAKWSRLLSPLIW---CHNMVTL 283
Fly 284 GWAVRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAACAWWAVLCLGWHRD 348
Fly 349 IRRHSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNFVCF--VAWGLPAFQTSAVIVARFVD 411
Fly 412 ADELLGACFVGNQSDKALQILVATPVFCYWIF-GSMNLISGYLVHCRTKEILRNSNALSVQQQLQ 475
Fly 476 QLSAHSSSGIGIFLFIYGLACAMLLLAVIYEFANIDVW------------------LGSGDTNTP 522
Fly 523 LWPFLLRAFMELMLGICCFAWVLGPSIST----LYKRQ-----VSNGKMVKHTSAGAATGHLDGH 578
Fly 579 SSSRGSHAACNSTVVSYHSVRTSMASVPLPPSPYKLK-------------TSPGTGSISLNQMSN 630
Fly 631 YSLGRSVHHQQRHSP 645 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fz4 | NP_511068.2 | CRD_FZ4 | 43..169 | CDD:143557 | 41/122 (34%) |
| 7tm_4 | 223..544 | CDD:304433 | 78/353 (22%) | ||
| Fzd6 | NP_001155966.1 | CRD_FZ6 | 20..146 | CDD:143559 | 41/123 (33%) |
| 7tmF_FZD6 | 188..508 | CDD:320160 | 81/368 (22%) | ||
| TM helix 1 | 198..222 | CDD:320160 | 5/33 (15%) | ||
| TM helix 2 | 231..252 | CDD:320160 | 6/25 (24%) | ||
| TM helix 3 | 283..305 | CDD:320160 | 9/21 (43%) | ||
| TM helix 4 | 326..342 | CDD:320160 | 8/15 (53%) | ||
| TM helix 5 | 364..387 | CDD:320160 | 6/23 (26%) | ||
| TM helix 6 | 418..440 | CDD:320160 | 7/21 (33%) | ||
| TM helix 7 | 469..494 | CDD:320160 | 6/24 (25%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 498..503 | 1/4 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 583..709 | 2/11 (18%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||