DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fz4 and mfrp

DIOPT Version :9

Sequence 1:	NP_511068.2	Gene:	fz4 / 31659	FlyBaseID:	FBgn0027342	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_009289590.1	Gene:	mfrp / 101885305	ZFINID:	ZDB-GENE-160728-150	Length:	572	Species:	Danio rerio

Alignment Length:	128	Identity:	38/128 - (29%)
Similarity:	67/128 - (52%)	Gaps:	10/128 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SSSSPPEIPAFRQCETIRIEMCRKIGYNETSMPNL-VGNEMQTDVEYTLQTFAPLIEYDCSSQLK 96
            :|:.||...:   ||.|::||||.:.||.||.||: :....|.:....|..:..|::..|....:
Zfish   449 NSTYPPFTSS---CELIQVEMCRDLSYNLTSFPNIWLSLSDQREAASILHKYRVLVDLPCFESFR 510

  Fly    97 LFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETM 159
            ..:|..::|.|:|::.|..:  |:|:|.:..::|.|.|..|...||  .:|...|  ::|:.|
Zfish   511 QLVCGMFLPRCSPQSGVLQL--CQSVCSTAELQCSPALSLFSLNWP--FNCLLLP--DSHDPM 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fz4	NP_511068.2	CRD_FZ4	43..169	CDD:143557	35/118 (30%)
fz4	NP_511068.2	7tm_4	223..544	CDD:304433
mfrp	XP_009289590.1	CUB	138..248	CDD:238001
		LDLa	256..290	CDD:238060
		CUB	297..405	CDD:238001
		LDLa	413..447	CDD:238060
		Fz	459..563	CDD:279700	33/109 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900