Protein Alignment CG8300 and FAM177A1

DIOPT Version :9

• Sequence 1: NP_572384.1
• Gene: CG8300 / 31658
• FlyBaseID: FBgn0029937
• Length: 185
• Species: Drosophila melanogaster
• Sequence 2: NP_775878.2
• Gene: FAM177A1 / 283635
• HGNCID: 19829
• Length: 236
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 51/202 - (25%)
• Similarity: 90/202 - (44%)
• Gaps: 37/202 - (18%)

  Fly    14 AAGGLELASASGASASETDNVSALE----------LQSNKRMLYFSDG-VMEELSSGSEDEADAE 67
            ||.|...|:|.|.||.:..|....|          .:..:|:::|..| .|||.|: .|||.|
Human    39 AASGAAAAAAFGESAGQMSNERGFENVELGVIGKKKKVPRRVIHFVSGETMEEYST-DEDEVD-- 100

  Fly    68 MGDKCYDV--HLNESEMPLGPRLRYKASRMGNRFLAGIDYVGGGLAHLLGITSSKYASELENYHR 130
             |.:..||  .::.:::..||.|.:...|.....|:..|::|..:|.:|||::.||...::.|:|
Human   101 -GLEKKDVLPTVDPTKLTWGPYLWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYR 164

  Fly   131 -AKEHGDEDLDN---------WHPRAMST----------TTSSSNNNSSGNNNRNETIVLCEPTR 175
             .||..:|:.:|         :....:.|          |..||:..:.......::.|:.|..:
Human   165 MKKEEEEEEEENRMSEEAEKQYQQNKLQTDSIVQTDQPETVISSSFVNVNFEMEGDSEVIMESKQ 229

  Fly   176 SEATLPP 182
            :..::||
Human   230 NPVSVPP 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8300	NP_572384.1	FAM177	30..140	CDD:291440	34/123 (28%)
FAM177A1	NP_775878.2	FAM177	64..167	CDD:291440	29/106 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11491
eggNOG	1	0.900	-	-		E1_2AEPG
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	53	1.000	Inparanoid score	I5450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1572938at2759
OrthoFinder	1	1.000	-	-		FOG0004847
OrthoInspector	1	1.000	-	-		otm42223
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31206
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.930