Protein Alignment CG4617 and HMGXB4

DIOPT Version :9

• Sequence 1: NP_001259308.1
• Gene: CG4617 / 31657
• FlyBaseID: FBgn0029936
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: XP_006724164.1
• Gene: HMGXB4 / 10042
• HGNCID: 5003
• Length: 603
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 101/493 - (20%)
• Similarity: 170/493 - (34%)
• Gaps: 208/493 - (42%)

  Fly     2 ESPTSHLVAKDFQVTGVSRSGRVRKKSSK---------LLDFESPDEIEKRTRRHSGARQPARYS 57
            |..:|.:..:.||..  |:...|:|.|.|         ||..|....::...::|..:.......
Human   243 EKGSSSVDEESFQYP--SQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSP 305

  Fly    58 G-RGRPSNALR-------DLDLD--QEMLVDDGIISDSEEFHPDTTATVVAILNSDDELDN---L 109
            | .|..|:|.:       :|||.  :.:||:    |||               :|..||:.   :
Human   306 GPEGCGSDASQFAESHSANLDLSGLEPILVE----SDS---------------SSGGELEAGELV 351

  Fly   110 VQDIVDGVQAEATSQESSVRQSLYMREKSNKRQVLKD-----------GKVV------------- 150
            :.|....::.:..|::|..::.   :||..:::..|.           |:|.
Human   352 IDDSYREIKKKKKSKKSKKKKD---KEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAG 413

  Fly   151 -------------------SAKVQRKDKGKQR--------YTAYSLWAKEARQKDLQD---LDFT 185
                               ..|.:.|||.::|        .:||.::.||.|...:.|   :||.
Human   414 AAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFG 478

  Fly   186 SATRRLSELWANVSNRDKNTWRRKAKIEASRAKTRDKTAANGATQPASNGSTALADATQHETIFQ 250
            ..:::|:|:|..:..:||..|::||:.                              .||:   |
Human   479 ELSKKLAEVWKQLPEKDKLIWKQKAQY------------------------------LQHK---Q 510

  Fly   251 NRATTSRTRKLAADRQQSSIEAAAAAAAAAATGTNTQRRSISTRSARSQVSKSATKQAQVHTDAD 315
            |:|..:..:     |:.||.|.:....|::....:.|::|..|...
Human   511 NKAEATTVK-----RKASSSEGSMKVKASSVGVLSPQKKSPPTTML------------------- 551

  Fly   316 VSGRTGGQLKQEEVQKTSIEVIDAAAHLKLLGESLTVIGERLKKHNGYVALSGSLSVLLDSLLCA 380
                    |.....:....|.||.||||:||||||::||.||::
Human   552 --------LPASPAKAPETEPIDVAAHLQLLGESLSLIGHRLQE--------------------- 587

  Fly   381 MGPLLCMTTQIPGMENNVQLSKNLADTLDNIAYVMPGL 418
                         .|:|         |||||||:||||
Human   588 -------------TESN---------TLDNIAYIMPGL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4617	NP_001259308.1	HMG-box	165..218	CDD:238037	16/55 (29%)
HMGXB4	XP_006724164.1	DUF4171	150..268	CDD:290491	7/26 (27%)
		HMG-box	450..513	CDD:238037	20/95 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008243
OrthoInspector	1	1.000	-	-		oto91169
orthoMCL	1	0.900	-	-		OOG6_109229
Panther	1	1.100	-	-	LDO	PTHR46584
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5833
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.940