DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4615 and Mmd

DIOPT Version :9

Sequence 1:	NP_572382.1	Gene:	CG4615 / 31656	FlyBaseID:	FBgn0029935	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001382352.1	Gene:	Mmd / 67468	MGIID:	1914718	Length:	239	Species:	Mus musculus

Alignment Length:	247	Identity:	105/247 - (42%)
Similarity:	131/247 - (53%)	Gaps:	27/247 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 NVKWKNAKAKPGCAYQPTEIEQVANVITHGIWILPAVFAAIKLFERSSSASQYLVAWVYGGALCM 129
            |..:.|.:|.....|:||..|..||..||...|:||:..:..|...|....:.:.||:||..||.
Mouse     8 NTVFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAWIYGMGLCA 72

  Fly   130 LFTVSTFFHCSCYCAEHKPPKNVKAWPCLGWQTYQGLKNVLHRCDRAMIYVFIAGSYFPWLTLEN 194
            ||.|||.||...:...|                .:.:::..|.|||.:||.|||.||.|||.|..
Mouse    73 LFIVSTVFHIVSWKKSH----------------LRTVEHCFHMCDRMVIYFFIAASYAPWLNLRE 121

  Fly   195 ----TDHSAILFCMEWVIWLMAGIGIAYQQVFHERYKCLETFFYLVMGLGPALVVVFTGHHFHGM 255
                ..|      |.|.|||||..|..|..::||:||.:|.||||.||..|||||. :.::..|:
Mouse   122 LGPLASH------MRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVT-SMNNTDGL 179

  Fly   256 MQLKFGGGFYILGIVFFKADGTIPMAHAIWHLFVVLAAGCHYYAILVNLYPS 307
            .:|..||..|.||:||||:||.||.|||||||||..||..|||||...||.|
Mouse   180 QELACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRS 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4615	NP_572382.1	hlyIII	85..304	CDD:273425	96/222 (43%)
Mmd	NP_001382352.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	138	1.000	Domainoid score	I4820
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8204
Inparanoid	1	1.050	192	1.000	Inparanoid score	I3849
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487730at2759
OrthoFinder	1	1.000	-	-		FOG0003169
OrthoInspector	1	1.000	-	-		otm44178
orthoMCL	1	0.900	-	-		OOG6_103941
Panther	1	1.100	-	-	O	PTHR20855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3376
SonicParanoid	1	1.000	-	-		X2564
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.860