DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and HXT17

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_014470.1	Gene:	HXT17 / 855809	SGDID:	S000005355	Length:	564	Species:	Saccharomyces cerevisiae

Alignment Length:	461	Identity:	106/461 - (22%)
Similarity:	199/461 - (43%)	Gaps:	69/461 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 TQPFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDR 141
            |..::|:........::.::.|.:|||:.:...|.:||:..|::..|:.::|.|:.::| .|.
Yeast    98 TGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISS-NHK-- 159

  Fly   142 DMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR- 205
               :||..:|:...|:..|.......:..:||:...:||.|:....|.:..||.|.||..|..|
Yeast   160 ---WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRK 221

  Fly   206 --HNIQLIFGISCCYQLAATLLVFPM---PESPSWLLTRGKEERARKSLRYFRGLPKKE---VDY 262
              :..|....:..|: |...:::..|   ||||.:|:...:.|.||.|:.....:..::   :..
Yeast   222 YDNTAQWRVPLGLCF-LWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQ 285

  Fly   263 VPEFEAELAHMKELADAS---NTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYA 324
            ..|..|.:...:||.:||   ..:...:.|.::|      ..:|:.|    |.|..|......|.
Yeast   286 ADEINAGVLAQRELGEASWKELFSVKTKVLQRLI------TGILVQT----FLQLTGENYFFFYG 340

  Fly   325 VQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFP 389
            ..|.:..|:| |....:::||.....:|:....:.:|.||:...:|.|.||.|||::.|.
Yeast   341 TTIFKSVGLT-DGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFAS----- 399

  Fly   390 DTLGTLHWLPVACIVAH--------------IVFSTMGML-------TLPFFMISEVFPQRARGS 433
                    :.|.|:..|              |||:...:.       .:.:.:::|.||.:.:..
Yeast   400 --------IGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSR 456

  Fly   434 ASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGV--FVPETRGRTLEELE 496
            |..|:.....:..|::....|.:   .|:.:.:..|..:..|.|.|:.|  |:|||.|.:|||::
Yeast   457 AMSISTACNWLWQFLIGFFTPFI---TGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQ 518

  Fly   497 ERWQTG 502
            ..::.|
Yeast   519 LLYEEG 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	97/441 (22%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	104/452 (23%)
HXT17	NP_014470.1	Sugar_tr	60..521	CDD:395036	105/456 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740