Protein Alignment CG4607 and VBA1

DIOPT Version :9

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_013806.1
• Gene: VBA1 / 855113
• SGDID: S000004694
• Length: 562
• Species: Saccharomyces cerevisiae
• Alignment Length: 626
• Identity: 121/626 - (19%)
• Similarity: 205/626 - (32%)
• Gaps: 239/626 - (38%)

  Fly     5 QEEQLVPPP--AYKPTVVAKDTTKDSHAKEKPLGEGRLAVLRQELMVFLGNSGVLGSGMVVSMPA 67
            :...|:|||  |..|.:            |:...|..||:.:..::..|.....| |.:..::.|
Yeast     6 ETSNLLPPPEEAEAPPL------------EQKFHEYNLALPKFPILFSLWLGSFL-SSLDSTIVA 57

  Fly    68 VTLNQLHDETQPFWLNKDESSWFAS---IQNMAC-PLGGLLVSYFLDRIGRKHTILLTNLIGLIG 128
            ..:|::.:|    :....:..|.|:   :.|.|. ||.|.|    .|..|||..:|.......:|
Yeast    58 NIMNRVAEE----FSESSKKQWIATSFLLTNTAFQPLYGKL----SDITGRKSALLTAQFFFGLG 114

  Fly   129 WILLVTSFMHSDRDMIYYQMLLGRCFGGI--MIGMFVSPV------GVYSAEISLPKIRGRLILG 185
              .|:|.|..:..:....:.:.|...||:  :..:.||.:      |||....::....|:| ||
Yeast   115 --CLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQL-LG 176

  Fly   186 TSLGLASGILLMYCLGYFIRH-NIQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSL 249
            ..||           |.||.. ..:.:|||.....:..::|                   |.|::
Yeast   177 APLG-----------GVFIETIGWRALFGIQVPVIMLCSVL-------------------AIKNI 211

  Fly   250 RYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQA 314
            ..       ::.:||.       |||.....|           :.|.:::..:.::.|..|....
Yeast   212 NI-------KLFHVPP-------MKERYTLKN-----------LSRIDIFGSLSLVATISGVLFL 251

  Fly   315 CG----------------VVVIIV---YAVQ-----------IAQQAGVTI------------DP 337
            |.                :|.|:|   ||.:           ....:.||:            .|
Yeast   252 CSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFELLTRSFCLSSAVTVISSFVVFGEIFRSP 316

  Fly   338 VLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHW----- 397
            :.:.::..::...|.||:  ||      || |..|.|.     |:.|            |
Yeast   317 IYLQLLQNISVTKTGLFL--IF------PS-ISVAVGS-----LVTG------------WVLRNT 355

  Fly   398 -LPVACIVAHIVFSTMGM----LTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNME 457
             :.:|.....|:|..|.|    |.|.:|::|.:.|.                     ..||..:|
Yeast   356 KINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPD---------------------YTIYDMLE 399

  Fly   458 AALGTAN-----LFAFYAG--ISF-----LAAAFIGVFVPETRGRTLEELEERWQTGKF------ 504
            :....:|     |...:|.  :||     |.|..:.:..      |:|:.::...||.|
Yeast   400 SITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVF------TVEKSQQGTMTGVFYLWRSI 458

  Fly   505 ----SRRLTIVNL----------------KDVELHEVFLKK 525
                ...||:|:.                :|.|.|  |.||
Yeast   459 GNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYH--FTKK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	96/505 (19%)
		SP	67..495	CDD:273317	96/504 (19%)
VBA1	NP_013806.1	MFS_Azr1_MDR_like	42..469	CDD:341045	104/546 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900