DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and HXT11

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_014486.1	Gene:	HXT11 / 854009	SGDID:	S000005516	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	508	Identity:	128/508 - (25%)
Similarity:	218/508 - (42%)	Gaps:	67/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EKPLGE-GRLAVLRQELMVFLG------NSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSW 89
            :|||.. ..:|:|.  ||:..|      ::|.: ||.|.....:......::...::|:|.....
Yeast    52 QKPLSAYTTVAILC--LMIAFGGFIFGWDTGTI-SGFVNLSDFIRRFGQKNDKGTYYLSKVRMGL 113

  Fly    90 FASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCF 154
            ..||.|:.|.:||:::|...|..||:..::....|.::|.::.:||...      :||..:||..
Yeast   114 IVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINK------WYQYFIGRII 172

  Fly   155 GGIMIG--MFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR--HN-IQLIFGI 214
            .|:.:|  ..:||:.:  :|::...|||.|:....|....||.|.||..|..:  || .|...|:
Yeast   173 SGLGVGGIAVLSPMLI--SEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGL 235

  Fly   215 SCCYQLAATLLVFPM---PESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKEL 276
            ..|:.. ||.:|..|   ||||.:|:..||:|.|::||.....:...:...:.|::...|.: ||
Yeast   236 GLCFAW-ATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGI-EL 298

  Fly   277 ADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVA 341
            ...:...:..|.||.   :.:|::.|||.......||..|......|...|.:..|:. |....:
Yeast   299 EKLAGNASWSELLST---KTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLK-DSFQTS 359

  Fly   342 VMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHWLPVA----- 401
            :::||....::.......|::||:...::.|..|..|..:.|       ::|.....|..
Yeast   360 IIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFA-------SVGVTKLWPQGSSHQD 417

  Fly   402 --------CIVAHIVFSTMGMLTL----PFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYP 454
                    |::...:|......|.    .:.::||.||.|.:.....||.....:..|::....|
Yeast   418 ITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTP 482

  Fly   455 NMEAALGTANLFAFYAGISFL-----AAAFIGVFVPETRGRTLEELEERWQTG 502
            .:..|:.      ||.|..||     |..::..|||||:|.||||:...|..|
Yeast   483 FITGAIN------FYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEG 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	108/458 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	113/457 (25%)
HXT11	NP_014486.1	Sugar_tr	64..526	CDD:395036	122/491 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740