Protein Alignment CG4607 and VPS73

DIOPT Version :10

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 446
• Identity: 102/446 - (22%)
• Similarity: 191/446 - (42%)
• Gaps: 63/446 - (14%)

  Fly    74 HDETQPFWLNK----------DESSWFASIQNMACPLGGLLVSYFLDRI----GRKHTILLTNLI 124
            :|.|   ||.|          ||.  ...:.::.| :||:|.|||...:    |||.:.|:...:
Yeast    70 YDRT---WLGKRGYKQCIPLNDEQ--IGIVTSVFC-IGGILGSYFATSLANIYGRKFSSLINCTL 128

  Fly   125 GLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLG 189
            .::|.:::..|       ..|..:::||...||..|..:..:.::..|::.....|.|...|.:.
Yeast   129 NIVGSLIIFNS-------NSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQIC 186

  Fly   190 LASGILLMYCLGYFIRHNIQ---LIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRY 251
            :..|:||...:...:..:.:   ::|| |....:....:.|.:.|||.|||..|:...|:.||..
Yeast   187 IRLGVLLTQGIALPLTDSYRWRWILFG-SFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCK 250

  Fly   252 FRGLPKKE-VDYVPEFEAELAHMKELAD--ASNTTAAGESLSQMIH-RPEVYKPVLMMTTFFGFQ 312
            .||:...| ...:.:::.::.....|.:  .:|:.:...||.:.:. |..|....::....|| |
Yeast   251 LRGVTFDEAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFG-Q 314

  Fly   313 QACGVVVIIVYAVQIAQQAGVTIDP---VLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATG 374
            |.||:..|::|..:|..|    :.|   :.:...:.:..::.|:.:|.:.....|||. :.::|.
Yeast   315 QFCGINSIVLYGTKIISQ----LYPQHAIRINFFISMVNVLVTILVSLLIHSLPRKPL-LMTSTV 374

  Fly   375 MGACMLLLAGGNWFPDTLGTLHWLPVACIVAHIVFS-------TMGMLTLPFFMISEVFPQRARG 432
            :.:....:.|.....:.:..|           ||||       |||:..|||.::.||...:...
Yeast   375 LVSVTAFIMGIAMNHNKMNLL-----------IVFSFIYMGVFTMGLNPLPFIIMREVSKPQDMV 428

  Fly   433 SASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETR 488
            .|.........:..||:...:|.:...| :..:|..:|.|:...:|||...||||:
Yeast   429 LAQRYGTICNWVGTFIIAYTFPIIHDVL-SGYVFIIFAIIACSISAFIWKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS_GLUT6_8_Class3_like	47..494	CDD:340916	102/446 (23%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	102/446 (23%)