DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and HXT7

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	445	Identity:	115/445 - (25%)
Similarity:	205/445 - (46%)	Gaps:	45/445 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 WLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIY 145
            :|:|..:....||.|:.|.:||:::|...|..|||..:::..:|.:||.|:.:.|...      :
Yeast   109 YLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINK------W 167

  Fly   146 YQMLLGRCFGGIMIG--MFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR--- 205
            ||..:||...|:.:|  ..:||:.:  :|:|...:||.|:....|.:.:||.|.||..:..:
Yeast   168 YQYFIGRIISGLGVGGIAVLSPMLI--SEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYS 230

  Fly   206 HNIQLIFGISCCYQLAATL---LVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFE 267
            :::|....:..|:..|..:   :.| :||||.:|...||.|.|::|:.....:...:...:.|.|
Yeast   231 NSVQWRVPLGLCFAWALFMIGGMTF-VPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVE 294

  Fly   268 AELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAG 332
            |.||.: |....:...:.||..|.   :.:|.:.::|.......||..|......|...|.:..|
Yeast   295 AVLAGV-EAEKLAGNASWGELFSS---KTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVG 355

  Fly   333 VTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLA---------GGNWF 388
            :: |....:::||:....:|.....:.|::||:...::.|..|.|||::.|         .|...
Yeast   356 LS-DSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQ 419

  Fly   389 PDTLGTLHWLPV-ACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKI 452
            |.:.|..:.:.| ||.......:|..  .:|:.::||.||.|.:..|..||.....:..|::...
Yeast   420 PSSKGAGNCMIVFACFYIFCFATTWA--PIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFF 482

  Fly   453 YPNMEAALGTANLFAFYAGISFLAAA-----FIGVFVPETRGRTLEELEERWQTG 502
            .|.:..|:.      ||.|..|:...     ::.:.||||:|.||||:...|:.|
Yeast   483 TPFITGAIN------FYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEG 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	104/425 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	112/436 (26%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	113/440 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342983
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740