DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and HXT15

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_010036.1	Gene:	HXT15 / 851352	SGDID:	S000002404	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	460	Identity:	104/460 - (22%)
Similarity:	197/460 - (42%)	Gaps:	67/460 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 TQPFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDR 141
            |..::|:........::.::.|.:||:..:...|.:||:..|::..|:.::|.|:.::| .|.
Yeast   101 TGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISS-NHK-- 162

  Fly   142 DMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR- 205
               :||..:|:...|:..|.......:..:||:...:||.|:....|.:..||.|.||..|..|
Yeast   163 ---WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRK 224

  Fly   206 --HNIQLIFGISCCYQLAATLLV--FPMPESPSWLLTRGKEERARKSLRYFRGLPKKE---VDYV 263
              :..|....:..|:..|..::|  ..:||||.:|:...:.|.|..|:.....:..::   :...
Yeast   225 YSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQA 289

  Fly   264 PEFEAELAHMKELADAS---NTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAV 325
            .|..|.:...:||.:||   ..:...:.|.::|      ..:|:.|    |.|..|......|..
Yeast   290 DEINAGVLAQRELGEASWKELFSVKTKVLQRLI------TGILVQT----FLQLTGENYFFFYGT 344

  Fly   326 QIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPD 390
            .|.:..|:| |....:::||.....:|:....:.:|.||:...:|.|..|.|||::.|.
Yeast   345 TIFKSVGLT-DGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFAS------ 402

  Fly   391 TLGTLHWLPVACIVAH--------------IVFSTMGML-------TLPFFMISEVFPQRARGSA 434
                   :.|.|:..|              |||:...:.       .:.:.:::|.||.:.:..|
Yeast   403 -------IGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKA 460

  Fly   435 SGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGV--FVPETRGRTLEELEE 497
            ..|:..|..:..|::....|.:   .|:.:.:..|..:..|.|.|:.|  |:|||.|.:|||::.
Yeast   461 MSISTAFNWLWQFLIGFFTPFI---TGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQL 522

  Fly   498 RWQTG 502
            .::.|
Yeast   523 LYEEG 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	95/440 (22%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	102/451 (23%)
HXT15	NP_010036.1	MFS_HXT	62..524	CDD:340914	103/455 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740