DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and HXT10

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	523	Identity:	129/523 - (24%)
Similarity:	220/523 - (42%)	Gaps:	85/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQ------------PFWLNKDESSWFASIQNMACP 99
            ||:..|       |.:......|::...::|.            .|.|:...:.....|.|:.|.
Yeast    54 LMIAFG-------GFIFGWDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGLIVGIFNIGCA 111

  Fly   100 LGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVS 164
            ||||.:....|..|||..::...|:.::|.::.:.|   ||:   :||..:||    |:.||.|.
Yeast   112 LGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIAS---SDK---WYQYFIGR----IVSGMGVG 166

  Fly   165 PVGVYS----AEISLPKIRGRLILGTSLGLASGILLMYCLGYFIR---HNIQLIFGISCCYQLAA 222
            .|.|.|    :|||...:||..:....|.:..||.|.||..|..:   ::||....:..|:..|.
Yeast   167 GVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAI 231

  Fly   223 TLLV--FPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAA 285
            .:::  ..:||||.:|:.:||.|.||:||.....:...:...|.||:..:|:| ||..|....:.
Yeast   232 FMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANM-ELERAVGNASW 295

  Fly   286 GESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARII 350
            .|..|   ::..:...|:|.......||..|......|...|....|:. |....:::||.....
Yeast   296 HELFS---NKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQ-DSFETSIVLGAVNFA 356

  Fly   351 TTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHWLP--------------VA 401
            :|.....|.:|:||:...::.:..|..|.::.|       |:|.....|              :.
Yeast   357 STFVALYIVDKFGRRKCLLWGSASMAICFVIFA-------TVGVTRLWPQGKDQPSSQSAGNVMI 414

  Fly   402 CIVAHIVFS-TMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANL 465
            ......:|| .:....:.:.:::|.:|.|.:..|..||:....:..|::....|.:..::|.:..
Yeast   415 VFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYG 479

  Fly   466 FAFYAGISFLAAAFIGVFVPETRGRTLEEL----EER---WQTGKF---SRR---------LTIV 511
            :.| .|....:..::..||.||:|.||||:    |||   |::|.:   |||         |.||
Yeast   480 YVF-MGCLIFSYFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIV 543

  Fly   512 NLK 514
            :.|
Yeast   544 DSK 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	105/464 (23%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	112/463 (24%)
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	117/487 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342993
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830