DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and SGB1

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_178100.3	Gene:	SGB1 / 844321	AraportID:	AT1G79820	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	131/533 - (24%)
Similarity:	211/533 - (39%)	Gaps:	93/533 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKGQQEEQLVPPPAY------------KPTVVAKDTTKDSHAKEKP----------LGEGRLAVL 43
            |:|:..::.||...:            .||...||....|..:..|          |....|.|:
plant    11 MRGRHIDKRVPSKEFLSALDKAETAVRLPTGTGKDCGNPSWKRSLPHVLVASLTSLLFGYHLGVV 75

  Fly    44 RQEL---MVFLGNSG-VLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSWFASIQNMACPLGGLL 104
            .:.|   .:.||.|| .:..|:|||                                .|..|..:
plant    76 NETLESISIDLGFSGNTIAEGLVVS--------------------------------TCLGGAFI 108

  Fly   105 VSYF----LDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSP 165
            .|.|    .|.:||:....|:.|..::|     .|...|...::  .|||||...||.:|:..|.
plant   109 GSLFSGLVADGVGRRRAFQLSALPMIVG-----ASVSASTESLM--GMLLGRFLVGIGMGIGPSV 166

  Fly   166 VGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNI---QLIFGISCCYQLAATLLVF 227
            ..:|..|:|...:||.....|.:....|:|.....|...:.|:   ::.|.||..  .||.|.||
plant   167 TALYVTEVSPAYVRGTYGSSTQIATCIGLLGSLFAGIPAKDNLGWWRICFWISTV--PAAMLAVF 229

  Fly   228 P--MPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLS 290
            .  ..|||.||..||:...|........|     ..||....|||.......||.:.     .||
plant   230 MELCVESPQWLFKRGRAAEAEAVFEKLLG-----GSYVKAAMAELVKSDRGDDADSA-----KLS 284

  Fly   291 QMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVA-VMLGVARIITTLF 354
            :::. ...::.|.:.:|.|..||..|:..:..::..:.::|||   |...| :.:||..::.:..
plant   285 ELLF-GRSFRVVFIGSTLFALQQLSGINAVFYFSSTVFKKAGV---PSASANICVGVCNLLGSTV 345

  Fly   355 MSGIFEKWGRKPSGIFSATGMGACMLLLA-GGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLP 418
            ...:.:|.|||...|.|..||...:.|.| .....|...||| :|.|..::..::....|...:|
plant   346 AVVLMDKLGRKVLLIGSFAGMAVSLGLQAIAYTSLPSPFGTL-FLSVGGMLLFVLSFATGAGPVP 409

  Fly   419 FFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVF 483
            ..::||:.|.|.|.:|..:.:....::.|.:..::..|...||:..|.|.:.....:|..|:...
plant   410 SLLLSEICPGRLRATALAVCLAVHWVINFFVGLLFLRMLEQLGSVLLNAIFGFFCVVAVIFVQKN 474

  Fly   484 VPETRGRTLEELE 496
            |.||:|::|:|:|
plant   475 VVETKGKSLQEIE 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	107/440 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	107/438 (24%)
SGB1	NP_178100.3	MFS_GLUT_like	60..477	CDD:340873	115/472 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810