DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and INT2

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_174313.1	Gene:	INT2 / 839902	AraportID:	AT1G30220	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	138/562 - (24%)
Similarity:	226/562 - (40%)	Gaps:	141/562 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VLRQELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSWFAS-IQNMACP---LGG 102
            |||   :.|....|.|..|....:.:..|..:.|:    :.:.|.::|... |.:||..   :|.
plant    28 VLR---LAFSAGIGGLLFGYDTGVISGALLYIRDD----FKSVDRNTWLQEMIVSMAVAGAIVGA 85

  Fly   103 LLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVG 167
            .:..:..|::||:..||:.:.:.|:|.|::..:...|       .:::||.|.|:.:||......
plant    86 AIGGWANDKLGRRSAILMADFLFLLGAIIMAAAPNPS-------LLVVGRVFVGLGVGMASMTAP 143

  Fly   168 VYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNIQLIF-----------GISCCYQLA 221
            :|.:|.|..||||.|: .|:..|.:|       |.|:.:.|.|.|           ||:....|.
plant   144 LYISEASPAKIRGALV-STNGFLITG-------GQFLSYLINLAFTDVTGTWRWMLGIAGIPALL 200

  Fly   222 ATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAG 286
            ..:|:|.:||||.||..:|:||.|:..||        .:....:.|.|:   :.|.|:..|....
plant   201 QFVLMFTLPESPRWLYRKGREEEAKAILR--------RIYSAEDVEQEI---RALKDSVETEILE 254

  Fly   287 ESLSQMIHRPEVYKPVLMMTTFFG------FQQACGVVVIIVYAVQIAQQAG------------V 333
            |..|:.|:..::.|...:......      |||..|:..::.|:..|.|.||            |
plant   255 EGSSEKINMIKLCKAKTVRRGLIAGVGLQVFQQFVGINTVMYYSPTIVQLAGFASNRTALLLSLV 319

  Fly   334 T--------------IDPV-----LVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSA------- 372
            |              ||.:     |:..:.||  ||:...::|:|.:.......|.|.
plant   320 TAGLNAFGSIISIYFIDRIGRKKLLIISLFGV--IISLGILTGVFYEAATHAPAISSLETQRFNN 382

  Fly   373 -----------TGMGACMLLL------------------AGGNWFPD---------------TLG 393
                       |....||..|                  .|..|..|               |.|
plant   383 ISCPDYKSAMNTNAWDCMTCLKASSPSCGYCSSPIGKEHPGACWISDDSVKDLCHNENRLWYTRG 447

  Fly   394 ---TLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPN 455
               ...|..:..:..:|:|.:.||.|:|:.:.||::|.|.||...|||.....|...|:.:.:.:
plant   448 CPSNFGWFALLGLGLYIIFFSPGMGTVPWIVNSEIYPLRFRGICGGIAATANWISNLIVAQSFLS 512

  Fly   456 MEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEE 497
            :..|:||:..|..:..||.:|..|:.|.||||:|..:||:|:
plant   513 LTEAIGTSWTFLIFGVISVIALLFVMVCVPETKGMPMEEIEK 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	126/534 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	129/533 (24%)
INT2	NP_174313.1	SP	25..552	CDD:273317	136/558 (24%)
INT2	NP_174313.1	MFS	33..541	CDD:119392	127/539 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810