DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and slc2a1

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001072458.1	Gene:	slc2a1 / 779913	XenbaseID:	XB-GENE-5755357	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	126/507 - (24%)
Similarity:	226/507 - (44%)	Gaps:	80/507 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGRLAVLRQELMVFLGNSGVLGSGM---VVSMPAVTLNQLHDETQPFWLNK-----DESS----W 89
            ||::.. |..|.|.....|.|..|.   |::.|...:...::.|   ||.:     .||:    |
Frog     4 EGKMTA-RLMLAVCTAVIGSLQFGYNTGVINAPQEVIEGFYNAT---WLERYNEPIPESTLTSLW 64

  Fly    90 FASIQNMACPLGGLLVSY----FLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLL 150
            ..|:...:  :||::.|:    |::|.||::::|:.|::..:..||:..|.:....:|    :::
Frog    65 SLSVAIFS--VGGMVGSFSVGLFVNRFGRRNSMLMANVLAFLAAILMGFSKLAVSFEM----LII 123

  Fly   151 GRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGT--SLGLASGILLMYCLGYFIRHNIQLIFG 213
            ||...|:..|:....|.:|..|:|...:||  .|||  .||:..|||:....|      ::.|.|
Frog   124 GRFVVGLYCGLTTGFVPMYVGEVSPTSLRG--ALGTLHQLGVVVGILIAQIFG------LKPIMG 180

  Fly   214 --------ISCCYQLAATL--LVFPM-PESPSWLL-TRGKEERARKSLRYFRGLPKKEVDYVPEF 266
                    :.|.: :.|.|  ::.|. ||||.:|| .|.:|::|:..|:..||        ..:.
Frog   181 NDSLWPFLLGCIF-IPAILQCIMLPFCPESPRFLLINRNEEDKAKSVLKKLRG--------TTDV 236

  Fly   267 EAELAHMKELADASNTTAAGESLSQM---------IHRPEVYK-PVLMMTTFFGFQQACGVVVII 321
            .::|..|||           ||...|         :.|..:|: |:.:.......||..|:..:.
Frog   237 SSDLQEMKE-----------ESRQMMREKKVTILELFRSPLYRQPMFIAIILQLSQQLSGINAVF 290

  Fly   322 VYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGN 386
            .|:..|.|:|.|. .||...:..|:.....|:....:.|:.||:...:....||..|.:|:....
Frog   291 YYSTMIFQKAQVE-QPVYATIGAGIVNTAFTVVSLFVVERAGRRTLHLIGLGGMAVCAILMTIAL 354

  Fly   387 WFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLK 451
            ...|::|.:.:|.:..|...:.|..:|...:|:|:::|:|.|..|.:|..:|........||:..
Frog   355 ALLDSVGGMSYLSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGLSNWTSNFIVGM 419

  Fly   452 IYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGK 503
            .:..:|...| |.:|..:..:..:...|....||||:|||.:|:...::.|:
Frog   420 GFQYVEQLCG-AYVFIIFTVLLLIFFVFTYFKVPETKGRTFDEIASEFRQGE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	112/468 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	114/464 (25%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	118/482 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000