back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and Slc2a5

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_113929.1	Gene:	Slc2a5 / 65197	RGDID:	68328	Length:	502	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	139/524 - (26%)
Similarity:	235/524 - (44%)	Gaps:	78/524 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 KEKPLGEGRLAVLRQELMVFL---GNSGVLGSGM-VVSMPAVTLNQLHDETQPFWLNKDESSWFA 91
            ||.....|:|.:: ..|..||   |:|...|..: .|:.|:..:.|.:::|. :..||:....|.
  Rat     3 KEDQEKTGKLTLV-LALATFLAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTY-YDRNKENIESFT 65

  Fly    92 -----SIQNMACPLGG----LLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQ 147
                 |:.....|.||    |:|.:.::.:|||..:|..|:..::..||:..|.:....::|
  Rat    66 LTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKIAKSFEII--- 127

  Fly   148 MLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNI---- 208
             :..|...||..|:..:.|.:|..|::...:||.|.:...|.:..|||:....|  :|..:
  Rat   128 -IASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFG--LRSVLASEE 189

  Fly   209 --QLIFGISCCYQLAATLLVFP-MPESPSWLLTRGK-EERARKSLRYFRGLPKKEVDYVPEFEAE 269
              .::.|:: .......||:.| .||||.:||.:.| |..|.|:|:..||.  |:||...|   |
  Rat   190 GWPILLGLT-GVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGW--KDVDMEME---E 248

  Fly   270 LAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVT 334
            :....|...|:...:..:.......|.::...:::||.    ||..||..|..||.||...|||.
  Rat   249 IRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMTG----QQLSGVNAIYYYADQIYLSAGVK 309

  Fly   335 IDPV-LVAVMLGVARIITTLFMSGIFEKWGRKPSGIFS-ATGMGACMLL---LAGGNWFPDTLGT 394
            .:.| .|....|...:..|:....:.|.|||:...:.. :|.:.||::|   ||..|       |
  Rat   310 SNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIGFSTCLTACIVLTVALALQN-------T 367

  Fly   395 LHWLP---VACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNM 456
            :.|:|   :.|::.:::...:|...:|...|:|:|.|.:|.||..|......:..||:..|:|.:
  Rat   368 ISWMPYVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWLSNFIVGLIFPFI 432

  Fly   457 EAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRRLTIVNLKDVELHEV 521
            :..||..: |..:|.|..|.:.:|.:.||||:|||.                       ||::::
  Rat   433 QVGLGPYS-FIIFAIICLLTSIYIFMVVPETKGRTF-----------------------VEINQI 473

  Fly   522 FLKK 525
            |.||
  Rat   474 FAKK 477

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.