Protein Alignment CG4607 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 123/501 - (24%)
• Similarity: 226/501 - (45%)
• Gaps: 71/501 - (14%)

  Fly    43 LRQELMVFLGNSGVLGSGM------VVSMPAVTLNQLHDETQPFWLNKDESS---------WFAS 92
            |...||:.:|.: ||||..      |::.|...:.:.:::|   |:::...|         |..|
Human     8 LTGRLMLAVGGA-VLGSLQFGYNTGVINAPQKVIEEFYNQT---WVHRYGESILPTTLTTLWSLS 68

  Fly    93 IQNMACPLGGLLVSY----FLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRC 153
            :...:  :||::.|:    |::|.||::::|:.||:..:..:|:..|.:....:|    ::|||.
Human    69 VAIFS--VGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEM----LILGRF 127

  Fly   154 FGGIMIGMFVSPVGVYSAEISLPKIRGRLILGT--SLGLASGILLMYCLGYFIRHNIQLIFGISC 216
            ..|:..|:....|.:|..|:|...:||  .|||  .||:..|||:....|      :..|.|...
Human   128 IIGVYCGLTTGFVPMYVGEVSPTALRG--ALGTLHQLGIVVGILIAQVFG------LDSIMGNKD 184

  Fly   217 CYQLAATLLVFP----------MPESPSWLL-TRGKEERARKSLRYFRGLPKKEVDYVPEFEAEL 270
            .:.|..:::..|          .||||.:|| .|.:|.||:..|:..||            .|::
Human   185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRG------------TADV 237

  Fly   271 AH-MKELADASNTTAAGESLS--QMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAG 332
            .| ::|:.:.|......:.::  ::...|...:|:|:.......||..|:..:..|:..|.::||
Human   238 THDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAG 302

  Fly   333 VTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHW 397
            |. .||...:..|:.....|:....:.|:.||:...:....||..|.:|:.......:.|..:.:
Human   303 VQ-QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSY 366

  Fly   398 LPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGT 462
            |.:..|...:.|..:|...:|:|:::|:|.|..|.:|..:|.|......||:...:..:|...|.
Human   367 LSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGP 431

  Fly   463 ANLFAFYAGISFLAAAFIGVF--VPETRGRTLEELEERWQTGKFSR 506
               :.|......|...||..:  ||||:|||.:|:...::.|..|:
Human   432 ---YVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQ 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	109/465 (23%)
		SP	67..495	CDD:273317	110/458 (24%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	114/477 (24%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		3/5 (60%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840