DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and slc2a11b

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_005165088.1	Gene:	slc2a11b / 564970	ZFINID:	ZDB-GENE-070705-96	Length:	522	Species:	Danio rerio

Alignment Length:	551	Identity:	130/551 - (23%)
Similarity:	223/551 - (40%)	Gaps:	106/551 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 YKPTVVAKDTTKDSHAKEKPLGEGRLAVLRQELMVFLGNSGVLGSGM------VVSMPAVT---- 69
            |:|  :.:|..:..|         ::.|..:.|::.:..:|:.|:..      :::.|...
Zfish    22 YEP--LLRDFREPVH---------QIKVPSKYLLLAVWAAGIGGTFQYGYNISIINAPTKAVQNF 75

  Fly    70 LNQLHDETQPFWLNKDESSWFASIQNMACPLGGLLVS----YFLDRIGRKHTILLTNLIGLIGWI 130
            :||...|.....::.|..:...||......:|||:.:    ....|.|||.|:|..|...|:..:
Zfish    76 INQTWTERYSTEISSDMLTLLWSIIVSIFTIGGLVGASVGGTLAIRFGRKGTLLFNNTFALLAAL 140

  Fly   131 LLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGIL 195
            .:..|:..|..::    :::||...|:..|:.:....:|..||:...:||.:.:|||:.:..|||
Zfish   141 FMGLSYPASTFEL----LVIGRFLTGVNAGIAICVQPLYIGEIAPRALRGAMAMGTSIFITGGIL 201

  Fly   196 LMYCLGYFIRHNIQLIFG---------ISCCYQLAATLLVFP-MPESPSWLL-TRGKEERARKSL 249
            ....:|      ::.:.|         .:.|......||..| .||||.:|| .||.:...:|:|
Zfish   202 TGQVMG------LKELLGKDEYWPILLSTICIPAVLQLLTLPWFPESPRYLLIDRGDDIACQKAL 260

  Fly   250 RYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKP------------V 302
            .:|.|..|        :..|:..::.           |.:|.:..:|:  ||            :
Zfish   261 MWFHGQDK--------YHGEMEDIER-----------ERVSALGIKPK--KPWELFTDRSIRWQL 304

  Fly   303 LMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVA-VMLGVARIITTLFMSGIFEKWGRKP 366
            |.:......||..|:..|..||..:..|||:..|.:..| |..|....||.|....:.|..||:.
Zfish   305 LTLVVIHTSQQLNGINAIYFYADYVFTQAGIPDDKIPYATVGTGACECITALTCGLLIESLGRRA 369

  Fly   367 SGIFSATGMGACMLLLAGGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRAR 431
            ..|...|.|..|.:.......|.|:...:.:|.:.|::|.|:...:|...:...:.:|:|.|..|
Zfish   370 LIIGGYTLMSVCCICFTIALTFQDSSPWVPYLSMVCVLAFILSFGLGPGGVTNILTTELFTQTDR 434

  Fly   432 -------GSASGIAIF-FGMILAFIM--LKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPE 486
                   ||.:..:.| .|||..||:  ||.|           .|..:..|..|.|.:|...|||
Zfish   435 PAAYMIGGSINWTSFFVIGMIFPFIVNGLKQY-----------CFLVFLVICLLVATYIFFVVPE 488

  Fly   487 TRGRTLEELEERWQTGKFSRRLTIVNLKDVE 517
            |:.:|..|::     .:|..|..|:|....|
Zfish   489 TKNKTFLEIQ-----NEFKSRKKIINANGTE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	113/476 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	115/469 (25%)
slc2a11b	XP_005165088.1	Sugar_tr	54..501	CDD:278511	118/493 (24%)
slc2a11b	XP_005165088.1	MFS	98..486	CDD:119392	106/429 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840