DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	518	Identity:	125/518 - (24%)
Similarity:	213/518 - (41%)	Gaps:	103/518 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 MVFLGNSGVLGSGM------VVSMPAVTLNQLHDETQPFWLNKDESS---------W-FA----S 92
            ::|..::.|:||..      |::.|...|....:.|   |:.:....         | ||    |
Zfish    12 LLFSLSTAVIGSLQFGYNTGVINAPEQKLRAFFNAT---WMERYGEPISPGVCTIVWSFAVAIFS 73

  Fly    93 IQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGI 157
            :..||   |...|....::.||:.:::|.|::.|||..|:....:.|..:||    :.||...|:
Zfish    74 VGGMA---GSFSVGVVANKFGRRKSMILVNVLALIGGGLMGLCTLCSSFEMI----IAGRLMIGL 131

  Fly   158 MIGMFVSPVGVYSAEISLPKIRGRLILGT--SLGLASGILLMYCLGYFIRHNIQLIFGISCCYQL 220
            ..|:|.....:|..|:|...:||  ..||  .||:..|||:....|      ::.:.|....:.:
Zfish   132 FCGLFTGLTPMYVGEVSPTPLRG--AFGTLHQLGVVVGILIAQIFG------LESLLGSDKLWPI 188

  Fly   221 AATLLVFP----------MPESPSWLLTR-GKEERARKSLRYFRGLPK--KEVDYVPEFEAELAH 272
            ...|.:.|          .||||.:||.. .:||:|||:|...||...  |::..:.|..|::|.
Zfish   189 LLALTILPAILQCFLLPFCPESPRYLLINLNEEEQARKALVRLRGYEDVGKDMQEMKEESAKMAM 253

  Fly   273 MKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDP 337
            .|::       ...|......:|..::..:::..:    ||..|:..:..|:..|.:.|||| .|
Zfish   254 EKKV-------TIPELFRSAAYRQPLFIAIMLQLS----QQLSGINAVFYYSTGIFKSAGVT-QP 306

  Fly   338 VLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACML---------------------- 380
            :...:..||...:.|:....:.|:.||:...:....||....|
Zfish   307 IYATIGAGVVNTVFTVVSLFLVERAGRRTLHLIGLGGMAISALAMTIALLLVRFTVCFNFVKILN 371

  Fly   381 -----LLAGGNWF------PDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSA 434
                 |:...|.|      ...:..|.:|.:|.|.|.:....||...:|:|:::|:|.|..|.:|
Zfish   372 QPQQYLMIMVNVFITFVSKQKDIEALQYLSIAAIFAFVAMFEMGPGPIPWFIVAELFSQGPRPAA 436

  Fly   435 SGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVF--VPETRGRTLEEL 495
            ..:|........||:...:|.:|...|.   :.|...:.||...||..:  ||||:|||.:|:
Zfish   437 MAVAGCSNWTANFIVGITFPKLEELCGP---YVFIIFMIFLIIFFIFTYFKVPETKGRTFDEI 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	116/498 (23%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	118/491 (24%)
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	124/512 (24%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	102/429 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840