DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and CG4797

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	150/536 - (27%)
Similarity:	251/536 - (46%)	Gaps:	58/536 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QLVPPPAYKPTVVAKDTTKDSHAKEKPLGEGRLAVLRQELMVFLGNSGVL----GSGMVVSMPAV 68
            |:||...::....:..:.|.|...|:   :...|..|..:...|....||    |.||.:...|:
  Fly    20 QVVPGSEFQCKKASYSSRKLSTIDEQ---DDDAANRRGMMHQILATCAVLLLSAGCGMPIGFSAI 81

  Fly    69 TLNQLHDETQ---PFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWI 130
            .|.||.|...   |  ::.:..||.||:.::|.|.|.||.....|.:||:.|::|:.:..|:||.
  Fly    82 LLPQLMDNNSTEIP--IDVETGSWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWS 144

  Fly   131 LLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGIL 195
            .|  :...|.:.:|:.:.|   |  |...|:...|..||.||.:.|.:|..||....:..:||||
  Fly   145 TL--AIAKSIKVVIFARFL---C--GFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGIL 202

  Fly   196 LMYCLGYFIRHNIQLIFGISCC---YQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPK 257
            ::|.||     ::.....::.|   ..|.:.:.:..:||:|:|||..|.|:||.::|.:.||
  Fly   203 MVYSLG-----SMMYWRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEKRALQALSFLRG--- 259

  Fly   258 KEVDYVPEFEAELAHMKELADASN-------TTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQAC 315
                      :|::..|||.|...       ||...|::.|:..:....||::::..|...|...
  Fly   260 ----------SEISAQKELNDMKQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFS 314

  Fly   316 GVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACML 380
            |..::|.|||.:..:.|...|....|:...|.|:|..:....:.....|:...|.|..|.|...|
  Fly   315 GTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCL 379

  Fly   381 LLA---GGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFG 442
            :|:   ...:....:....::...|::.:|:|:| .::.:|..||.|:||.|.||..:| .:|..
  Fly   380 VLSVYQYARFDQPKMSYDVFVGAGCLLGYIIFNT-ALMVMPGIMIGELFPARIRGRTAG-GVFAS 442

  Fly   443 MILA-FIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELE-----ERWQT 501
            |.:| ||..|.:|.::|.|....:|..:...|||..||:.:|.|||:||:||.:|     :.|..
  Fly   443 MNVALFIFAKKFPALQAMLKMRGVFLVFGVSSFLLTAFMCLFQPETKGRSLEHIEDYFNGDNWLW 507

  Fly   502 GKFSRRLTIVNLKDVE 517
            .:..|....|||:.:|
  Fly   508 FRRDRGYKTVNLQPLE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	126/449 (28%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	129/444 (29%)
CG4797	NP_726368.2	MFS	64..484	CDD:119392	126/448 (28%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	124/436 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D104662at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920