DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and Slc2a12

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_849265.2	Gene:	Slc2a12 / 353169	MGIID:	3052471	Length:	622	Species:	Mus musculus

Alignment Length:	496	Identity:	104/496 - (20%)
Similarity:	196/496 - (39%)	Gaps:	122/496 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 MACPLGGLLVSYFLDRIGRKHTILLTN-LIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMI 159
            :|...||:|:    ||.||:..|:|:: |:|| |.::|:.|       :.|..:::||...|:.|
Mouse    96 LASLTGGVLI----DRYGRRLAIILSSCLLGL-GSLVLIMS-------LSYTLLIMGRVAIGVSI 148

  Fly   160 GMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYF---IRHNIQLIFGISCCYQLA 221
            .:......||.|||:....||.|:....|.:.:|||..|...|.   |.:..:.:||:.....:.
Mouse   149 SLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVL 213

  Fly   222 ATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMK-ELADASNTT-- 283
            ..:.::.:|.||.:|:.:|:||.|.|.||..|        .:.:...||..:| .|.|....:
Mouse   214 QAIAMYFLPPSPRFLVMKGQEESAGKVLRKLR--------VISDTTEELTLIKSSLKDEYQYSFW 270

  Fly   284 AAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPV--LVAVMLGV 346
            ....|...|..|      :|:..|...|.|..|...|:.||..:.:..|...:..  |.:..:||
Mouse   271 DLFRSKDNMRTR------ILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGV 329

  Fly   347 ARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLL----------------------------- 382
            .::::|:..:.:.:..|.|......::.|.|.:|.:
Mouse   330 VKVVSTIPATLLVDHIGSKTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFV 394

  Fly   383 ------------------------AGGNWFP-------------------------------DTL 392
                                    :.|::.|                               ||.
Mouse   395 FYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTA 459

  Fly   393 ---GTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYP 454
               ....||.:|.::.::...::|:..:|:.::||:||...||.|..:.......:..::...:.
Mouse   460 VVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFL 524

  Fly   455 NMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEEL 495
            .:...:|.:.:...|..:|..:.||:.:|:|||:|.:||::
Mouse   525 TVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQI 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	97/483 (20%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	104/494 (21%)
Slc2a12	NP_849265.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Sugar_tr	48..569	CDD:278511	104/496 (21%)
		MFS	49..>367	CDD:119392	76/296 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834447
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750