DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and ght6

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_587739.1	Gene:	ght6 / 2538845	PomBaseID:	SPCC1235.13	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	544	Identity:	125/544 - (22%)
Similarity:	209/544 - (38%)	Gaps:	107/544 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VLRQELMVFLGNSGVLGSGMVVSMPAVT---------LNQLHDETQPFWLNKDESSWFASIQNMA 97
            :|...::||:..:|.:......|:..:|         .::....|..:..:.........:.|..
pombe     4 ILTIVMLVFVSMAGWMFGADTGSIGGITNMRDFQSRYADRYDPVTDTYSYSSARQGLLVGMVNTG 68

  Fly    98 CPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMF 162
            ..:|.||.|...||.|::..|:...|:.:.|.|:.:|:...      :.||::.:.:.|:.||..
pombe    69 TTVGCLLSSPLGDRFGKRKCIMGWTLVYITGVIVQLTTIPS------WVQMMVAKIWTGLGIGAL 127

  Fly   163 VSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGY----FIRH---------NIQLIFGI 214
            ......|.:|.|.|.|||.::....|.:..||.:..|:..    :..|         .|.|::||
pombe   128 SVIAPGYQSESSPPHIRGAIVTTYQLFITLGIFIAACINMGTHKYTTHPEAQWRVPIGINLLWGI 192

  Fly   215 SCCYQLAATLLVFPM---PESPSWLLTRGKEERARKSLRYFRGLP------KKEVDYV-PEFEAE 269
                     |:.|.|   ||||.:|..:|:.|...|.|....|||      :||.:.: .:.|||
pombe   193 ---------LMFFGMLFLPESPRYLAVKGRNEECMKILTRNAGLPADHPIMQKEYNAIQADVEAE 248

  Fly   270 LAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFG-----FQQACGVVVIIVYAVQIAQ 329
            |              ||...|.    |:::...:...|..|     |||..|......|..|:.:
pombe   249 L--------------AGGPCSW----PQIFSNEIRYRTLLGMGVMAFQQLTGNNYFFYYGTQVFR 295

  Fly   330 QAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLA--GGNWFPDTL 392
            ..|:. .|.|.|::|.......|.....:.|.:||:...|........|..:.|  |........
pombe   296 GTGLN-SPFLAALILDAVNFGCTFGAIFVLEYFGRRGPLIVGGVWQSICFFIYASVGDRALTRPN 359

  Fly   393 GTLHWLPVACIVAHIVFSTMGMLTL-------PFFMISEVFPQRARGSASGIAI----FFGMILA 446
            ||.:....|.:   ||||.:.:.:.       .:.::.|.:|.|.|...:.:|.    |:..:::
pombe   360 GTSNHRAGAVM---IVFSCLFIFSFAQTWAPAAYVIVGESYPIRYRSKCAAVATASNWFWNFMIS 421

  Fly   447 FIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEE-------RWQTGKF 504
            |..    |.:..::|....:.| |..:..||..|.:|..||:|.||||:.:       .|.||.:
pombe   422 FFT----PFISNSIGFKYGYVF-AACNLCAAIIIFLFAKETKGLTLEEINQLYLSNIKPWNTGAY 481

  Fly   505 SRRLTIVNLKDVE--------LHE 520
            .|....:...|.|        |||
pombe   482 QRDREDIKQSDSEKERGPTSKLHE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	105/478 (22%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	110/477 (23%)
ght6	NP_587739.1	MFS	10..453	CDD:119392	107/484 (22%)
ght6	NP_587739.1	Sugar_tr	11..469	CDD:278511	115/499 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900