DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and ght1

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_587747.1	Gene:	ght1 / 2538732	PomBaseID:	SPCC548.07c	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	517	Identity:	109/517 - (21%)
Similarity:	210/517 - (40%)	Gaps:	74/517 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LMVFLGNSGVLGSGMVVSMPAVT---------LNQLHDETQPFWLNKDESSWFASIQNMACPLGG 102
            :::|:..:|.:......|:..:|         .::.:..|..:..:.........:.|:....|.
pombe     9 MLLFVSMAGWMFGADTGSIGGITNMRDFQSRFADRYNPVTDTYSYSSARQGLITGMVNVGSFFGC 73

  Fly   103 LLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVG 167
            |:.|...||||::::|:...:|.|||.|:.||:...      :.|:::.:.:.|:.||.......
pombe    74 LISSPTTDRIGKRNSIIGFCVIYLIGVIIQVTAVPS------WVQIMVAKIWTGLGIGALSVLAP 132

  Fly   168 VYSAEISLPKIRGRLILGTSLGLASGILLMYCLG-----------YFIRHNIQLIFGISCCYQLA 221
            .|.:|::.|.|||.:::...|.:.:||.:..|:.           :.:...|.|::||
pombe   133 GYQSEVAPPHIRGTIVVTYQLCVTAGIFIAACINMGTHKLYKTAQWRVSIGINLLWGI------- 190

  Fly   222 ATLL-VFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAA 285
            .||: |..:.|||.:|::.||::.|.:.:       .|..:..|:.:......|::.........
pombe   191 ITLVGVSFLSESPRYLVSIGKDDEAIQVM-------CKNAELPPDSDIIQTEYKQIKSDCEAAVE 248

  Fly   286 GESLSQMIHRPEVYKPVLMMTTFFG-----FQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLG 345
            |...:.    ||::...:...||.|     |.|..|......|..|:.:..|:. .|.|.:::|.
pombe   249 GGPCTW----PEIFGKEIRYRTFLGMAIMSFNQLTGCNYYFYYGTQVFKGTGME-SPYLASLILD 308

  Fly   346 VARIITTLFMSGIF--EKWGRKPSGIFSATGMGACMLLLA--GGNWFPDTLGTLHWLPVACIVAH 406
            ......|  ..|:|  |..||:...|........|..:.|  |........||.:....|.:
pombe   309 AVNFGCT--FGGLFVLEYCGRRVPLIIGGVWQSICFFIYAAVGNRALTRKNGTSNHRAGAVM--- 368

  Fly   407 IVFSTMGMLTL-------PFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTAN 464
            ||||.:.:.:.       .:.::.|.:|.|.|...:.:|.....:..|::....|.:..::|...
pombe   369 IVFSCLFIFSFAQTWGPAAYVIVGESYPIRYRSKCAAVATTSNWLWNFLISFFTPFITNSIGFKY 433

  Fly   465 LFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGK---FSRRLTIVNL---KDVELHE 520
            .:.| |..:..|:....:|..|::|.||||:.|.:.:..   .||...:..:   |:||..|
pombe   434 GYIF-ASCNLCASIVTFLFAHESKGLTLEEINELYLSDAKPWMSRPKNLSEMAEAKEVEREE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	94/465 (20%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	98/464 (21%)
ght1	NP_587747.1	MFS	10..452	CDD:119392	95/472 (20%)
ght1	NP_587747.1	Sugar_tr	11..467	CDD:278511	103/486 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900