DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and Slc2a2

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_037011.2	Gene:	Slc2a2 / 25351	RGDID:	3705	Length:	522	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	136/509 - (26%)
Similarity:	226/509 - (44%)	Gaps:	61/509 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 HAKEKPLGEGRLAVLRQELMVFLGNSGVLGSGM-VVSMPAVTLNQLHDETQPFWLNKDESS---- 88
            |....||.:.|..:          |..:.|:.. ::..||.|       |...|..:.|.|
  Rat    44 HVLGVPLDDRRATI----------NYDINGTDTPLIVTPAHT-------TPDAWEEETEGSAHIV 91

  Fly    89 ---WFASIQNMACPLGGLLVSYF----LDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYY 146
               |..|:.:.|  :||::.|:|    .|::||...:|..|.:.|.|.:|:..|.......:|
  Rat    92 TMLWSLSVSSFA--VGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALI-- 152

  Fly   147 QMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGT--SLGLASGILLMYCLGY-FIRHN- 207
              :.||...|:..|:....|.:|..||:...:||  .|||  .|.|.:|||:....|. ||..|
  Rat   153 --IAGRSVSGLYCGLISGLVPMYIGEIAPTTLRG--ALGTLHQLALVTGILISQIAGLSFILGNQ 213

  Fly   208 --IQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEE-RARKSLRYFRGLP--KKEVDYVPEFE 267
              ..::.|:|....|...||:...||||.:|..:.:|| ||:|||:..||..  .|:::
  Rat   214 DYWHILLGLSAVPALLQCLLLLFCPESPRYLYLKLEEEVRAKKSLKRLRGTEDVTKDIN------ 272

  Fly   268 AELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAG 332
             |:...||.|    :|....|:.|:...|...:|:::.......||..|:..|..|:..|.|.||
  Rat   273 -EMRKEKEEA----STEQKVSVIQLFTDPNYRQPIVVALMLHLAQQFSGINGIFYYSTSIFQTAG 332

  Fly   333 VTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHW 397
            :: .||...:.:|...:|.|.....:.||.||:...:....||..|.:.::.|....|....:.:
  Rat   333 IS-QPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLAGMIGMFFCAVFMSLGLVLLDKFTWMSY 396

  Fly   398 LPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGT 462
            :.:..|...:.|..:|...:|:||::|.|.|..|.:|..:|.|...:..||:...:..:...||
  Rat   397 VSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFIIALCFQYIADFLG- 460

  Fly   463 ANLFAFYAGISFLAAAFIGVFVPETRGRTLEEL--EERWQTGKFSRRLTIVNLK 514
            ..:|..:||:..:...|....||||:|::.:|:  |.|.::|....|...|.::
  Rat   461 PYVFFLFAGVVLIFTLFTFFKVPETKGKSFDEIAAEFRKKSGSAPPRKAAVQME 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	120/449 (27%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	123/447 (28%)
Slc2a2	NP_037011.2	MFS_GLUT_Class1	12..488	CDD:340989	129/481 (27%)
Slc2a2	NP_037011.2	Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	312..318		3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850