Protein Alignment CG4607 and hmit-1.1

DIOPT Version :9

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 132/600 - (22%)
• Similarity: 230/600 - (38%)
• Gaps: 133/600 - (22%)

  Fly    28 SHAKEKPLGEGRLAVLRQELMVFLGNSGVLGS---GMVVSMPAVTLNQLHDETQPFWLNKDESSW 89
            |..::||....:|.:    .:..|..:.|:|.   |...|:.:..:..:.|..   .|...::.|
 Worm     9 SSGQDKPAHTPKLGL----FVYILAAASVIGGFLFGYDTSVVSAAMLYMPDAP---GLKPMDTVW 66

  Fly    90 ---FASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLG 151
               ..||......:|.|:.....|.|||:..||..:.|..||.::...|       :....:|:|
 Worm    67 QEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAAS-------VNKIMLLVG 124

  Fly   152 RCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLG----YFIRHNI--QL 210
            |...||.||.....|.||..|.:...:||.|:...:|.::.|.::....|    |...:|:  :|
 Worm   125 RVLLGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGWRL 189

  Fly   211 IFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDY----VPEFEAELA 271
            :|..:....:...:....:||:|.||...|.|...|:.|.......|:.|:|    :..|..:.|
 Worm   190 MFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVYNGDKEWVEYEMAEIIAFNEDQA 254

  Fly   272 HMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTID 336
            ...|.|.||     |..:.:::..|.|.|...:.:....|||..|:..|:.|...|.:.:|::.:
 Worm   255 KENEKAHAS-----GPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNN 314

  Fly   337 --PVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSA-------TGMGACMLLL---------- 382
              .:.::|:|.:...|.......:.||.||:...:||.       ..:|...||:
 Worm   315 HTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPA 379

  Fly   383 --AGGNW---FPDTLGTL----------------------------------------------- 395
              .|.|:   :||..|.:
 Worm   380 NQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNS 444

  Fly   396 --------HW-----------LP-VACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIF 440
                    .|           || :||.|..:.||: |..:||:.:.||.:|..||.:...|:..
 Worm   445 NGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSS-GFTSLPWVLNSEFYPMWARSTCVAISTT 508

  Fly   441 FGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELE------ERW 499
            ...:...|:...|.::...:|....|..|||::.:|..||...||||:|.::||:|      ::.
 Worm   509 SNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVEMLFMNKKQR 573

  Fly   500 QTGKFSRRLTIVNLK 514
            :..:..||.|:..::
 Worm   574 REAESRRRETVTEVR 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	116/535 (22%)
		SP	67..495	CDD:273317	118/531 (22%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	117/538 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820