DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and C35A11.4

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_504430.2	Gene:	C35A11.4 / 178921	WormBaseID:	WBGene00016431	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	480	Identity:	110/480 - (22%)
Similarity:	205/480 - (42%)	Gaps:	76/480 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GSGMVVSMPAVT-----LNQ---------LHDET-QPFWLNKDESSWFASIQNMACPLGGLLVSY 107
            |..:|::.|:..     :||         |.|.| |..|      |:..:|..:....|...:..
Worm    25 GFNLVLTNPSQEAFLNFMNQTLAKRFDGGLSDNTLQNIW------SFVVAILFLGALAGSFSIRL 83

  Fly   108 FLDRIGRKHTILLTNLIG-LIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSA 171
            ..|.||||:.:.::..:| |.|.:.:.:.|:     .::...:..|...|..:.:.:....::.:
Worm    84 IADWIGRKNGLYISIAVGVLAGGMSIASKFI-----PLFELYIASRIVMGWSVSVSLGLSALFLS 143

  Fly   172 EISLPKIRGR--LILGT--SLGLASGILL----------MYCLGYFIRHNIQLIFGISCCYQLAA 222
            |.|..:.||.  ::.||  .||...|.::          ::.|.|.....|.|.||        |
Worm   144 EASPKQNRGAIGMMTGTCVQLGTVCGSVIAMPQIFGTEDLWWLIYATEIGIMLFFG--------A 200

  Fly   223 TLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGE 287
            .|..|  ||||.:|:.||..|.|.||:.|:...   |:|     ||| .|:.|:.:....:....
Worm   201 ALPFF--PESPGFLIQRGATEAATKSIAYYYNC---EID-----EAE-KHLNEIKEEQKNSTKNF 254

  Fly   288 SLSQMIHRPEVYKPV---LMMTTFFGFQQACGVVVIIVYAVQIAQQAGV-TIDPVLVAVMLGVAR 348
            .:..::.:..:....   :::|....|.   ||.||..:|..|.:..|: .::..|....:.|..
Worm   255 KMMDIVRKKSLRDKAFIGVVVTFAMSFS---GVAVINAFAFDILKDTGLKVLEASLANDAISVVS 316

  Fly   349 IITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAG--GNWFPDTLGTLHWLPVACIVAHIVFST 411
            :|:::..:.|.::.||:|..:.|..|:..|.|::..  ..::......|.::.:..|.....|..
Worm   317 MISSIVAAVIVDRNGRRPLLLISFAGILVCNLIIFALMFTFYKFENHVLGFILICFICIFTFFFA 381

  Fly   412 MGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTA--NLFAFYAGISF 474
            :|...|.:|:.:|:..|.||.:|...|....|:..|:::..:..|:..||.|  .|..|.|.:
Worm   382 LGPGPLCYFINAELVGQAARSAAQSWASVIQMLSRFVIVTAFLPMKNQLGEAWSYLILFVAPV-- 444

  Fly   475 LAAAFIGVF--VPETRGRTLEELEE 497
             ||:.:.::  :|||:.:...|:||
Worm   445 -AASLVYLYFSLPETKNKNPFEVEE 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	104/465 (22%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	104/467 (22%)
C35A11.4	NP_504430.2	MFS_GLUT_Class1_2_like	13..461	CDD:340915	107/471 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850