DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4607 and F13B12.2

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_501925.2	Gene:	F13B12.2 / 177935	WormBaseID:	WBGene00008730	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	508	Identity:	111/508 - (21%)
Similarity:	205/508 - (40%)	Gaps:	94/508 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQPF-----------WLNKDESS--WFASI--Q 94
            |..:||:....:|.|.:.|....|.||......|.|           .|:|.|.|  |..::  |
Worm    27 QGKVVFICLITILLSILPVGYYIVLLNVPEKVFQAFIFDHFENIFGLQLSKTEESLVWSLTVSSQ 91

  Fly    95 NMACPLGGLLVSYFLDRIGRKHTIL-LTNLIGLIGWILLVTSFMHSDRDMIYYQM--LLGRCFGG 156
            .:...:|.|:||. :.:.|.|..:: |.|:|.:.|.:|:..|:      .|.:.:  ::||...|
Worm    92 GVGALIGCLIVSP-ISKFGAKDVLMRLNNVILIAGSLLMFLSY------WITFPIAFIVGRILTG 149

  Fly   157 IMIGMFVSPVGVYSAEISLPKIRGRL--------ILGTSLGLASGILLMYCLGYFIRHNIQLI-- 211
            :..|:..:...:|..:|....|:|.:        ..|:|||....:..|:  |......|.::
Worm   150 VYTGLACAFAPLYLQQIIPKNIKGSMSCFLHIAVCFGSSLGAIFSLPFMF--GSETTWPILVVLP 212

  Fly   212 --FGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLP--------KKEVDYVPEF 266
              |||   ..|||:..:   |::|:.||..|:...|.:|::::..:.        |:..|.|||.
Worm   213 AGFGI---IMLAASYFI---PDTPNNLLQMGRYTEAIESIKFYYDIEDSDEDEIIKEYWDMVPEM 271

  Fly   267 EAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQA 331
            ..:|:.....:::|            |.|..:...|:..|..|.     |.:|.|.|:.::.:
Worm   272 PEQLSLCSAFSNSS------------IRRGILLGMVVSATQIFS-----GSMVTISYSTEMFE-- 317

  Fly   332 GVTIDPVLVAVMLGVARIITTLFMSGIFEKW----GRKPSGIFSATGMGACMLLLAGGNWF---- 388
            .|:...:||..:..:..|::.|...... :|    ||:|  :...|.| .|::    .|.|
Worm   318 AVSFIDILVPFLPALGSILSILLTIPAL-RWVETRGRRP--LLLKTLM-FCII----ANVFLLIF 374

  Fly   389 ----PDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIM 449
                .|:.|...|...|....:.:...:|:..:.:|:.:|:.|..|..::.|.|:....|.....
Worm   375 TLISSDSSGWASWGFAAAFFMYGIGYNLGVGPVAYFLPAELVPPEAASASLGAAVAVNWICTITT 439

  Fly   450 LKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGR-TLEELEERWQT 501
            ...|..:...:|..:...|....| :.:..:...:|||:.. .::.||.|..|
Worm   440 TLFYYPLSKTVGGWSYLIFIIPTS-IFSMILWRLLPETKFHYKIDPLEIRLLT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	101/478 (21%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	101/478 (21%)
F13B12.2	NP_501925.2	MFS_GLUT_Class1_2_like	34..479	CDD:340915	104/487 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920