Protein Alignment CG4607 and hmit-1.3

DIOPT Version :9

• Sequence 1: NP_572380.1
• Gene: CG4607 / 31653
• FlyBaseID: FBgn0029932
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 120/563 - (21%)
• Similarity: 212/563 - (37%)
• Gaps: 137/563 - (24%)

  Fly    53 NSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSW---FASIQNMACPLGGLLVSYFLDRIGR 114
            ::|::.:.|:....|..:..|            :|.|   ..||......:|.|......|.:||
 Worm    45 DTGIVSAAMLYVPNASGIKPL------------DSVWQEIIVSITPGVAAIGSLCSGPGSDFLGR 97

  Fly   115 KHTIL---LTNLIGLI----GWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAE 172
            |..|:   :|..||.|    .|..::              :|:||...|:.||.....|.:|.:|
 Worm    98 KKIIIGASVTFTIGAIICAAAWTKII--------------LLIGRILLGLAIGFASMIVPIYVSE 148

  Fly   173 ISLPKIRGRLILGTSLGLASGILLMYCLG----YFIRHNI--QLIFGISCCYQLAATLLVFPMPE 231
            .|...|||:|:.|..|.:..|:::...:|    |.....:  :|:|..:....:...:....:||
 Worm   149 ASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLMFAFAAVPAIIQFVCFLFLPE 213

  Fly   232 SPSWLLTRGKEERARKSL-RYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHR 295
            ||.||...|:...||:.| |.:.| ..:.|||... |...::.:||...:.....|.::.:::..
 Worm   214 SPRWLYEHGRTVEAREVLTRIYNG-HTEWVDYEIN-EISFSYEEELRAKAEHAGNGPTIIRILKT 276

  Fly   296 PEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARI--ITTLFMSGI 358
            |.|.|.:::.:....|||..|:..::.|...|.:.|||..:...:.:.:|.:.|  :.|.....:
 Worm   277 PHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIAL 341

  Fly   359 FEKWGRKPSGIFSATG-------MGACMLLLAGG------------NWFPDTL------------ 392
            .|:.||:...:.|..|       ||...||:...            |:.|...
 Worm   342 VERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCD 406

  Fly   393 ----------------------------------------------GT-LHW-----------LP 399
                                                          || ..|           ||
 Worm   407 FCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWEDTYCHTKFTVLP 471

  Fly   400 VACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTAN 464
            :..:|.:::..:.|...||:.:.:|.:|..||.:|..::.....|...|:...:.::..|.....
 Worm   472 IIIMVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYG 536

  Fly   465 LFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRR 507
            .|..|.|.:.:|..|:..|||||:|.:::|:|..:.| |..||
 Worm   537 TFFIYCGCTMVALVFVFFFVPETKGYSIDEVEMLFMT-KEERR 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	108/536 (20%)
		SP	67..495	CDD:273317	112/535 (21%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:421695	110/540 (20%)
		MFS	<190..>249	CDD:421695	17/60 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740