DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4607 and Slc2a13

DIOPT Version :9

Sequence 1:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_598295.2	Gene:	Slc2a13 / 171147	RGDID:	621814	Length:	637	Species:	Rattus norvegicus

Alignment Length:	578	Identity:	130/578 - (22%)
Similarity:	215/578 - (37%)	Gaps:	172/578 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RLAVLRQELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSWFASIQNMACPLGGL 103
            ||..:.|||:|    ||.:|:..|.::....||                             |.|
  Rat   103 RLGAMWQELLV----SGAVGAAAVAALAGGALN-----------------------------GAL 134

  Fly   104 LVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGV 168
                     ||:..|||.:.:..:|..:|..:   ::::    .:|.||...|:.||:....|.|
  Rat   135 ---------GRRSAILLASALCTVGSAVLAAA---ANKE----TLLAGRLVVGLGIGIASMTVPV 183

  Fly   169 YSAEISLPKIRGRLILGTSLGLASG----ILLMYCLGYFIRHNIQLIFGISCCYQLAATLLVFPM 229
            |.||:|.|.:||||:...:|.:..|    .::.....|..:...:.:.|::....:...|....:
  Rat   184 YIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFL 248

  Fly   230 PESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIH 294
            ||||.||:.:|:.::||:.|...||  .:.:|  .|:::....::|  :....:|||..:.:|:.
  Rat   249 PESPRWLIQKGQTQKARRILSQMRG--NQTID--EEYDSIRNSIEE--EEKEASAAGPIICRMLS 307

  Fly   295 RPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTID--PVLVAVMLGVARIITTLFMSG 357
            .|...:.:.:......|||..|:..|:.|:..|.|.:||..|  .:.:|.:......|.||....
  Rat   308 YPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVW 372

  Fly   358 IFEKWGRKPSGIFSATGMGACMLLLAGGNWF---------------------------------- 388
            :.||.||:.....|..|....:.:||.|...
  Rat   373 LVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLD 437

  Fly   389 PD---------------------------------------TLGTLHWLPVAC-----------I 403
            ||                                       ....:||....|           :
  Rat   438 PDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGL 502

  Fly   404 VAHIVFSTMGMLTLPFFMISEVFPQRARGS----ASGIAIFFGMILAFIMLKIYPNMEAALGTAN 464
            |.::||...||..:|:.:.||::|..||.:    ::||...|.::::...|.          ||.
  Rat   503 VLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLH----------TAE 557

  Fly   465 LFAFYAGISFLAAAFIGV---FV----PETRGRTLEELEERWQTGKFSRRLTIVNLKD 515
            ...:| |..||.|.|..|   ||    |||:|:.|||:|     ..|..||......|
  Rat   558 YLTYY-GAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIE-----SLFDHRLCTCGTAD 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4607	NP_572380.1	MFS	55..484	CDD:119392	109/525 (21%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	114/528 (22%)
Slc2a13	NP_598295.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..38
		MFS	75..580	CDD:119392	117/542 (22%)
		Sugar_tr	78..598	CDD:278511	126/565 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337848
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X729
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750